Predicting and validating microRNA targets

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作者
Eric C Lai
机构
[1] University of California at Berkeley,545 Life Sciences Addition, Department of Molecular and Cell Biology and Howard Hughes Medical Institute
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关键词
miRNA Target; Plant miRNAs; Single Genome; Notch Target Gene; Neutral Target;
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摘要
Given that microRNAs select their targets by nucleotide base-pairing, it follows that it should be possible to find microRNA targets computationally. There has been considerable progress, but assessing success and biological significance requires a move into the 'wet' lab.
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