A comprehensive review of phytochemicals of Withania somnifera (L.) Dunal (Solanaceae) as antiviral therapeutics

被引：0
|
作者：
Fathima Zahraa Ozeer
Saraswathi Nagandran
Yuan Seng Wu
Ling Shing Wong
Annatasha Stephen
Michelle Felicia Lee
Jureerat Kijsomporn
Rhanye Mac Guad
Kalaivani Batumalaie
Habeebat Adekilekun Oyewusi
Amita Verma
Ekta Yadav
Sheryar Afzal
Mahendran Sekar
Vetriselvan Subramaniyan
Neeraj Kumar Fuloria
Shivkanya Fuloria
Md. Moklesur Rahman Sarker
机构：
[1] Sunway University,Department of Medical Education, School of Medical and Life Sciences
[2] Sunway University,Sunway Microbiome Centre, School of Medical and Life Sciences
[3] INTI International University,Faculty of Health and Life Sciences
[4] Universiti Malaya,Department of Pharmaceutical Life Sciences, Faculty of Pharmacy
[5] Metharath University,School of Nursing
[6] Universiti Malaysia Sabah,Department of Biomedical Science and Therapeutics, Faculty of Medicine and Health Science
[7] Sunway College Johor Bahru,Pre
[8] Universiti Teknologi Malaysia,University Programmes
[9] Universiti Teknologi Malaysia,Department of Biosciences, Faculty of Science
[10] The Federal Polytechnic,Enzyme Technology and Green Synthesis Group, Faculty of Science
[11] Sam Higginbottom University of Agriculture,Department of Science Technology, Biochemistry Unit
[12] Technology and Sciences,Bioorganic and Medicinal Chemistry Research Laboratory, Department of Pharmaceutical Sciences
[13] King Faisal University,Department of Biomedical Science, College of Veterinary Medicine
[14] Monash University Malaysia,School of Pharmacy
[15] Monash University,Department of Pharmacology, Jeffrey Cheah School of Medicine and Health Sciences
[16] AIMST University,Faculty of Pharmacy
[17] Gono University,Department of Pharmacy
来源：
Discover Applied Sciences | / 6卷
关键词：
Phytochemical; Antiviral; Withanolides; Molecular mechanism; Nanoparticles;
D O I：
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中图分类号：
学科分类号：
摘要：
Withanolides have been predicted to inhibit SARS-CoV-2 viral proteins.Withaferin A has been predicted to alter HSV DNA polymerase’s binding conformation.Withaferin A also suppressed HIV-1 transcription and replication.
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