Factors Associated with Suboptimal Antiretroviral Therapy Adherence to Dose, Schedule, and Dietary Instructions

被引：0
作者：
Lena Nilsson Schönnesson
Mark L. Williams
Michael W. Ross
Göran Bratt
Blair Keel
机构：
[1] Karolinska University Hospital,Infectious Disease Clinic, Gay Men’s Health Center, Department SÖS//Karolinska Institute
[2] University of Texas School of Public Health,Center for Health Promotion and Prevention Research
来源：
AIDS and Behavior | 2007年 / 11卷
关键词：
Adherence; Antiretroviral therapy; Psychological distress;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The purpose of this study was to assess the degree of suboptimal antiretroviral therapy adherence to dose, schedule, and dietary instructions and to examine the effects of extra-personal, intra-personal, and inter-personal factors on suboptimal adherence across the three types of instructions. Self-report and clinical data were collected from 193 sexually infected Swedish patients receiving ART. Effects of extra-personal, intra-personal, and inter-personal factors on suboptimal adherence were examined using multivariate logistic regression models. Suboptimal adherence to dose instructions was recorded in 12% of patients. Equivalent percentage for suboptimal adherence to schedule instructions was 37% and for suboptimal adherence to dietary instructions 58%. Anxiety was the only risk factor for suboptimal adherence to dose. Heavy pill burden was a risk factor for suboptimal adherence to schedule. Older age and HIV-related post-traumatic stress disorder (PTSD) symptoms decreased the risk of suboptimal adherence to schedule. No factors investigated had an effect on suboptimal adherence to dietary instructions. To improve adherence to dose and schedule instructions, clinicians caring for patients with HIV should assess and treat anxiety and be alert to HIV-related PTSD symptoms.
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页码：175 / 183
页数：8
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  • [11] Trotta M. P.(2001)Self-reported symptoms after initiation of a protease inhibitor in HIV-infected patients and their impact on adherence to HAART HIV Clinical Trials 2 38-45
  • [12] Murri R.(1998)Adherence to antiretroviral and Journal of Acquired Immune Deficiency Syndrome 18 117-125
  • [13] Castelli F.(2000) in HIV disease AIDS Care 12 387-398
  • [14] Narcisco P.(2000)The relationship of disease severity, health beliefs and medication adherence among HIV patients Journal of Acquired Immune Deficiency Syndrome 23 386-395
  • [15] Noto P.(2005)Predictors of self-reported adherence and plasma HIV concentrations in patients on multidrug antiretroviral regimens AIDS Care 17 493-504
  • [16] Bartlett J. A.(1999)Prediction of adherence to antiretroviral therapy: A one-year longitudinal study AIDS 13 1763-1769
  • [17] Bartlett J. A.(1979)Sociodemographic and psychological variables influencing adherence to antiretroviral therapy Psychosomatic Medicine 41 209-218
  • [18] DeMasi R.(2004)Impact of event scale: A measure of subjective stress AIDS Care 16 199-211
  • [19] Quinn J.(2002)The impact of psychiatric symptoms, drug use, and medication regimen on non-adherence to HIV treatment Clinical Infectious Diseases 35 1541-1548
  • [20] Beck A.(1998)The effect of race/ethnicity on the outcome of highly active antiretroviral therapy for human immunodeficiency virus type 1–infected patients General Hospital Psychiatry 20 345-352
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