Recombinant factor VIIa: use in fatal post partum hemorrhage — Indian experience case series and review of literature

被引:0
作者
Shailesh R. Singi
Evita Fernandez
Sunil T. Pandya
H. R. Badrinath
机构
[1] CARE Hospitals,
[2] Fernandez Hospital,undefined
[3] Fernandez Hospital,undefined
[4] Novo Nordisk India,undefined
来源
Indian Journal of Hematology and Blood Transfusion | 2009年 / 25卷
关键词
PPH; Hemorrhage; rFVIIa; Coagulation; Bleeding; NICE registry; NovoSeven;
D O I
暂无
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学科分类号
摘要
Postpartum hemorrhage is leading cause of maternal mortality and still remains a challenging condition to treat and hysterectomy may be required to control the bleeding once medical interventions fail. These strategies are not always successful and a direct approach in activating the coagulation system can be more effective and life saving. We describe here the mechanism of action of rFVIIa, review of literature and its use in 10 cases with different causes for PPH with good response.
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页码:1 / 5
页数:4
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[11]  
Bonnar J.(2005)Recombinant Factor VIIa for life threatening postpartum hemorrhage Br J Anaesth 94 592-176
[12]  
Sobieszczyk S.(2006)Recombinant factor VIIa in patients with coagulopathy secondary to anticoagulant therapy, cirrhosis, or severe traumatic injury: Review of safety profile Transfusion 46 919-300
[13]  
Bręborowicz G.H.(2001)Successful treatment of severe intra abdominal bleeding associated with disseminated intravascular coagulation using recombinant activated factor VII Br J Haematol 113 174-514
[14]  
Kale A.(2003)Successful treatment of life threatening postpartum hemorrhage with recombinant activated factor VII Obstet Gynecol 101 1174-562
[15]  
Bayhan G.(2004)Use of recombinant factor VIIa to treat life-threatening nonsurgical bleeding in a post-partum patient Br J Anaesth 93 298-229
[16]  
Kenet G.(2002)Successful use of recombinant factor VIIa for massive bleeding after cesarean section due to HELLP-Syndrome Acta Haematol 108 162-7
[17]  
Walden R.(2005)Use of Recombinant Factor VIIa for Massive Postpartum Hemorrhage: Case Series and Review of Literature J Pak Med Assoc 55 512-undefined
[18]  
Eldad A.(2005)Recombinant factor VIIa for life-threatening post-partum hemorrhage Br J Anaesth 95 558-undefined
[19]  
Martinowitz U.(2006)Successful treatment of life threatening bleeding after Cesarean Section with Recombinant Activated Factor VII Clin Appl Thrombosis/Hemostasis 12 227-undefined
[20]  
Martinowitz U.(2007)The use of recombinant activated factor VII in life-threatening postpartum hemorrhage Transfusion Alternatives in Transfusion Medicine 9 1-undefined