Enhanced 2,3-butanediol production by altering the mixed acid fermentation pathway in Klebsiella oxytoca

被引：0

作者：

Xiao-Jun Ji

He Huang

Shuang Li

Jun Du

Min Lian

机构：

[1] Nanjing University of Technology,College of Life Science and Pharmacy

来源：

Biotechnology Letters | 2008年 / 30卷

关键词：

2,3-Butanediol; Proton-suicide method;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Klebsiella oxytoca mutants were isolated from the wild type strain ME-303 after mutagenesis with UV coupled with diethyl sulfate and the following modified proton suicide method. By analyzing the activities of lactate dehydrogenase and phosphotransacetylase involved in lactic and acetic acid formation pathways and batch fermentation, one mutant, ME-UD-3, was isolated that produced 7.8% more 2,3-butanediol than ME-303 with the corresponding byproducts of lactic and acetic acid decreased by 88% and 92%, respectively.

引用

页码：731 / 734

页数：3

共 26 条

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