Inhibition of the checkpoint kinase Chk1 induces DNA damage and cell death in human Leukemia and Lymphoma cells

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作者
Christopher Bryant
Kirsten Scriven
Andrew J Massey
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[1] Vernalis R&D Ltd,
来源
Molecular Cancer | / 13卷
关键词
Chk1; Leukemia; Lymphoma; Kinase inhibitor; V158411;
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[41]   Berberine Induces Apoptotic Cell Death via Activation of Caspase-3 and-8 in HL-60 Human Leukemia Cells: Nuclear Localization and Structure-Activity Relationships [J].
Okubo, Shinya ;
Uto, Takuhiro ;
Goto, Aya ;
Tanaka, Hiroyuki ;
Nishioku, Tsuyoshi ;
Yamada, Katsushi ;
Shoyama, Yukihiro .
AMERICAN JOURNAL OF CHINESE MEDICINE, 2017, 45 (07) :1497-1511
[42]   rc cytokine-aided crosstalk between dendritic cells and natural killer cells together with doxorubicin induces a healer response in experimental lymphoma by downregulating FOXP3 and programmed cell death protein 1 [J].
Singh, Ranjeet ;
Gupta, Uttam ;
Srivastava, Prateek ;
Paladhi, Ankush ;
Sk, Ugir Hossain ;
Hira, Sumit Kumar ;
Manna, Partha Pratim .
CYTOTHERAPY, 2022, 24 (12) :1232-1244
[43]   Ginsenoside Rg1 Induces Apoptosis through Inhibition of the EpoR-Mediated JAK2/STAT5 Signalling Pathway in the TF-1/Epo Human Leukemia Cell Line [J].
Li, Jing ;
Wei, Qiang ;
Zuo, Guo-Wei ;
Xia, Jing ;
You, Zhi-Mei ;
Li, Chun-Li ;
Chen, Di-Long .
ASIAN PACIFIC JOURNAL OF CANCER PREVENTION, 2014, 15 (06) :2453-2459
[44]   The cardiac glycoside ZINC253504760 induces parthanatos-type cell death and G2/M arrest via downregulation of MEK1/2 phosphorylation in leukemia cells [J].
Min Zhou ;
Joelle C. Boulos ;
Sabine M. Klauck ;
Thomas Efferth .
Cell Biology and Toxicology, 2023, 39 :2971-2997
[45]   The cardiac glycoside ZINC253504760 induces parthanatos-type cell death and G2/M arrest via downregulation of MEK1/2 phosphorylation in leukemia cells [J].
Zhou, Min ;
Boulos, Joelle C. ;
Klauck, Sabine M. ;
Efferth, Thomas .
CELL BIOLOGY AND TOXICOLOGY, 2023, 39 (06) :2971-2997
[46]   Apoptosis of HL-60 human leukemia cells induced by Asiatic acid through modulation of B-cell lymphoma 2 family proteins and the mitogen-activated protein kinase signaling pathway [J].
Wu, Qiuling ;
Lv, Tingting ;
Chen, Yan ;
Wen, Lu ;
Zhang, Junli ;
Jiang, Xudong ;
Liu, Fang .
MOLECULAR MEDICINE REPORTS, 2015, 12 (01) :1429-1434
[47]   Potentiation of 1-β-D-arabinofuranosylcytosine-mediated mitochondrial damage and apoptosis in human leukemia cells (U937) overexpressing Bcl-2 by the kinase inhibitor 7-hydroxystaurosporine (UCN-01) [J].
Tang, L ;
Boise, LH ;
Dent, P ;
Grant, S .
BIOCHEMICAL PHARMACOLOGY, 2000, 60 (10) :1445-1456
[48]   Human T-lymphotropic virus 1 (HTLV-1)-associated lichenoid dermatitis induced by CD8+ T cells in HTLV-1 carrier, HTLV-1-associated myelopathy/tropical spastic paraparesis and adult T-cell leukemia/lymphoma [J].
Tokura, Yoshiki ;
Ito, Taisuke ;
Kawakami, Chika ;
Sugita, Kazunari ;
Kasuya, Akira ;
Tatsuno, Kazuki ;
Sawada, Yu ;
Nakamura, Motonobu ;
Shimauchi, Takatoshi .
JOURNAL OF DERMATOLOGY, 2015, 42 (10) :967-974