The Role of Protein and Carbohydrates for Long-Term Weight Control: Lessons from the Diogenes Trial

被引：0
作者：
Perez-Cornago A. [1 ]
van Baak M.A. [2 ,5 ]
Saris W.H.M. [2 ]
Martínez J.A. [1 ,3 ]
Astrup A. [4 ]
机构：
[1] Department of Nutrition, Food Science and Physiology, Center for Nutrition Research, University of Navarra, C/Irunlarrea 1, Pamplona
[2] Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht, University of Maastricht, Maastricht
[3] CIBER Fisiopatología Obesidad y Nutrición (CIBERObn), Instituto de Salud Carlos III, Madrid
[4] Department of Nutrition, Exercise and Sport, University of Copenhagen, Rolighedsvej 26, Frederiksberg C
[5] NUTRIM School for Nutrition, Toxicology and Metabolism, Department of Human Biology, Maastricht University, P.O.Box 616, Maastricht
来源：
Current Nutrition Reports | 2014年 / 3卷 / 4期
关键词：
Carbohydrates; Diet; Fatty acids; Glycemic index; Low-calorie diet; Metabolic syndrome; Nutrigenomics; Obesity; Overweight; Personalized nutrition; Protein; Weight loss; Weight maintenance;
D O I：
10.1007/s13668-014-0096-0
中图分类号：
学科分类号：
摘要：
Current therapies to manage obesity are based on energy restriction and physical activity promotion. However, the role of specific dietary components for long-term weight maintenance is under debate. This review aims to illustrate some lessons from the pan-European Diogenes study, a randomized, controlled dietary intervention study, which investigated the role of dietary protein and glycemic index (GI) on weight maintenance in overweight/obese European families. For 6 months, families were randomly assigned to five ad libitum weight-maintenance diets: low-protein (LP)/low-GI (LGI), LP/high-GI (HGI), high-protein (HP)/LGI, HP/HGI, and a control diet. The main result was that the HP/LGI diet was more successful for maintaining weight loss, and has beneficial effects on cardiometabolic risks. Outcomes regarding gender, age, the model of delivery, genetic factors, and benefits on insulin sensitivity, cardiovascular risk, bone turnover, and inflammation are also reported. © 2014, Springer Science+Business Media New York.
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页码：379 / 386
页数：7
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