TGFBR1*6A is not associated with prostate cancer in men of European ancestry

被引：0

作者：

B K Suarez

P Pal

C H Jin

R Kaushal

G Sun

L Jin

B Pasche

R Deka

W J Catalona

机构：

[1] Washington University School of Medicine,Department of Psychiatry

[2] Washington University School of Medicine,Department of Genetics

[3] Cancer Genetics Program,Center for Genome Information, Department of Environmental Health

[4] University of Cincinnati,Division of Hematology and Oncology, Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine

[5] Northwestern University,Department of Urology, Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine

[6] Northwestern University,undefined

来源：

Prostate Cancer and Prostatic Diseases | 2005年 / 8卷

关键词：

TGFBR1; association;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The TGFBR1*6A (*6A) variant in exon 1 of the TGFBR1 gene has been postulated as a putative tumor susceptibility allele in several studies. We have performed a case–control study in 537 men with histologically verified prostate cancer and in 488 unrelated controls to investigate the association of *6A with prostate cancer. Our results revealed that the frequency of the *6A allele does not differ in men with prostate cancer compared to healthy controls, even in a subset of age-matched cases and controls. There is no compelling evidence for an association of the *6A variant with prostate cancer.

引用

页码：50 / 53

页数：3

共 37 条

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