Tumor microenvironment in ovarian cancer peritoneal metastasis

被引:0
作者
Shuangshuang Mei
Xing Chen
Kai Wang
Yuxin Chen
机构
[1] Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University,
[2] Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University (Enze Hospital,undefined
[3] Taizhou Enze Medical Center Group),undefined
来源
Cancer Cell International | / 23卷
关键词
Ovarian cancer; Tumor microenvironment; Metastasis;
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摘要
Ovarian cancer (OC) is one of the most common gynecological malignancies with high morbidity and mortality. The peritoneum is one of the most common metastatic sites in ovarian cancer, involving large amounts of ascites. However, its mechanism is unclear. The peritoneal microenvironment composed of peritoneal effusion and peritoneum creates favorable conditions for ovarian cancer progression and metastasis. Here, we reviewed the peritoneal metastasis patterns and molecular mechanisms of ovarian cancer, as well as major components of the peritoneal microenvironment, peritoneal effusion, and immune microenvironment, and investigated the relationship between the peritoneal microenvironment and ovarian cancer metastasis.
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