High heterogeneity undermines generalization of differential expression results in RNA-Seq analysis

被引：0
|
作者：
Weitong Cui
Huaru Xue
Lei Wei
Jinghua Jin
Xuewen Tian
Qinglu Wang
机构：
[1] Qilu Medical University,Key Laboratory of Biomedical Engineering & Technology of Shandong High School
[2] Environmental Protection Research Institute of Light Industry,undefined
[3] Shandong Sport University,undefined
来源：
Human Genomics | / 15卷
关键词：
RNA sequencing; Differential expression; Heterogeneity; Reproducibility; Outlier; Tumor;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [31] IDEAS: individual level differential expression analysis for single-cell RNA-seq data
    Zhang, Mengqi
    Liu, Si
    Miao, Zhen
    Han, Fang
    Gottardo, Raphael
    Sun, Wei
    GENOME BIOLOGY, 2022, 23 (01)
  • [32] Fused inverse-normal method for integrated differential expression analysis of RNA-seq data
    Prasad, Birbal
    Li, Xinzhong
    BMC BIOINFORMATICS, 2022, 23 (01)
  • [33] Evaluation of methods for differential expression analysis on multi-group RNA-seq count data
    Min Tang
    Jianqiang Sun
    Kentaro Shimizu
    Koji Kadota
    BMC Bioinformatics, 16
  • [34] Fused inverse-normal method for integrated differential expression analysis of RNA-seq data
    Birbal Prasad
    Xinzhong Li
    BMC Bioinformatics, 23
  • [35] IDEAS: individual level differential expression analysis for single-cell RNA-seq data
    Mengqi Zhang
    Si Liu
    Zhen Miao
    Fang Han
    Raphael Gottardo
    Wei Sun
    Genome Biology, 23
  • [36] ARMOR: An Automated Reproducible MOdular Workflow for Preprocessing and Differential Analysis of RNA-seq Data
    Orjuela, Stephany
    Huang, Ruizhu
    Hembach, Katharina M.
    Robinson, Mark D.
    Soneson, Charlotte
    G3-GENES GENOMES GENETICS, 2019, 9 (07): : 2089 - 2096
  • [37] Effect of method of deduplication on estimation of differential gene expression using RNA-seq
    klepikova, Anna V.
    Kasianov, Artem S.
    Chesnokov, Mikhail S.
    Lazarevich, Natalia L.
    Penin, Aleksey A.
    Logacheva, Maria
    PEERJ, 2017, 5
  • [38] A Generalized dSpliceType Framework to Detect Differential Splicing and Differential Expression Events Using RNA-Seq
    Zhu, Dongxiao
    Deng, Nan
    Bai, Changxin
    IEEE TRANSACTIONS ON NANOBIOSCIENCE, 2015, 14 (02) : 192 - 202
  • [39] Physiological RNA dynamics in RNA-Seq analysis
    Xu, Zhongneng
    Asakawa, Shuichi
    BRIEFINGS IN BIOINFORMATICS, 2019, 20 (05) : 1725 - 1733
  • [40] SwarnSeq: An improved statistical approach for differential expression analysis of single-cell RNA-seq data
    Das, Samarendra
    Rai, Shesh N.
    GENOMICS, 2021, 113 (03) : 1308 - 1324
12345