High heterogeneity undermines generalization of differential expression results in RNA-Seq analysis

被引:0
|
作者
Weitong Cui
Huaru Xue
Lei Wei
Jinghua Jin
Xuewen Tian
Qinglu Wang
机构
[1] Qilu Medical University,Key Laboratory of Biomedical Engineering & Technology of Shandong High School
[2] Environmental Protection Research Institute of Light Industry,undefined
[3] Shandong Sport University,undefined
来源
Human Genomics | / 15卷
关键词
RNA sequencing; Differential expression; Heterogeneity; Reproducibility; Outlier; Tumor;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [21] Two-phase differential expression analysis for single cell RNA-seq
    Wu, Zhijin
    Zhang, Yi
    Stitzel, Michael L.
    Wu, Hao
    BIOINFORMATICS, 2018, 34 (19) : 3340 - 3348
  • [22] Parametric analysis of RNA-seq expression data
    Konishi, Tomokazu
    GENES TO CELLS, 2016, 21 (06) : 639 - 647
  • [23] Sensitivity, specificity, and reproducibility of RNA-Seq differential expression calls
    Paweł P. Łabaj
    David P. Kreil
    Biology Direct, 11
  • [24] Sensitivity, specificity, and reproducibility of RNA-Seq differential expression calls
    Labaj, Pawel P.
    Kreil, David P.
    BIOLOGY DIRECT, 2016, 11
  • [25] A Semi-parametric Bayesian Approach for Differential Expression Analysis of RNA-seq Data
    Fangfang Liu
    Chong Wang
    Peng Liu
    Journal of Agricultural, Biological, and Environmental Statistics, 2015, 20 : 555 - 576
  • [26] A Semi-parametric Bayesian Approach for Differential Expression Analysis of RNA-seq Data
    Liu, Fangfang
    Wang, Chong
    Liu, Peng
    JOURNAL OF AGRICULTURAL BIOLOGICAL AND ENVIRONMENTAL STATISTICS, 2015, 20 (04) : 555 - 576
  • [27] A statistical normalization method and differential expression analysis for RNA-seq data between different species
    Zhou, Yan
    Zhu, Jiadi
    Tong, Tiejun
    Wang, Junhui
    Lin, Bingqing
    Zhang, Jun
    BMC BIOINFORMATICS, 2019, 20 (1)
  • [28] Integrated analysis of single-cell RNA-seq and bulk RNA-seq unravels the heterogeneity of cancer-associated fibroblasts in TNBC
    Wu, Xiaoqing
    Lu, Wenping
    Zhang, Weixuan
    Zhang, Dongni
    Mei, Heting
    Zhang, Mengfan
    Cui, Yongjia
    Zhuo, Zhili
    AGING-US, 2023, 15 (21): : 12674 - 12697
  • [29] A statistical normalization method and differential expression analysis for RNA-seq data between different species
    Yan Zhou
    Jiadi Zhu
    Tiejun Tong
    Junhui Wang
    Bingqing Lin
    Jun Zhang
    BMC Bioinformatics, 20
  • [30] Evaluation of methods for differential expression analysis on multi-group RNA-seq count data
    Tang, Min
    Sun, Jianqiang
    Shimizu, Kentaro
    Kadota, Koji
    BMC BIOINFORMATICS, 2015, 16