High heterogeneity undermines generalization of differential expression results in RNA-Seq analysis

被引：0
|
作者：
Weitong Cui
Huaru Xue
Lei Wei
Jinghua Jin
Xuewen Tian
Qinglu Wang
机构：
[1] Qilu Medical University,Key Laboratory of Biomedical Engineering & Technology of Shandong High School
[2] Environmental Protection Research Institute of Light Industry,undefined
[3] Shandong Sport University,undefined
来源：
Human Genomics | / 15卷
关键词：
RNA sequencing; Differential expression; Heterogeneity; Reproducibility; Outlier; Tumor;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [1] High heterogeneity undermines generalization of differential expression results in RNA-Seq analysis
    Cui, Weitong
    Xue, Huaru
    Wei, Lei
    Jin, Jinghua
    Tian, Xuewen
    Wang, Qinglu
    HUMAN GENOMICS, 2021, 15 (01)
  • [2] Robustness of differential gene expression analysis of RNA-seq
    Stupnikov, A.
    McInerney, C. E.
    Savage, K. I.
    McIntosh, S. A.
    Emmert-Streib, F.
    Kennedy, R.
    Salto-Tellez, M.
    Prise, K. M.
    McArt, D. G.
    COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2021, 19 : 3470 - 3481
  • [3] An empirical likelihood ratio test robust to individual heterogeneity for differential expression analysis of RNA-seq
    Xu, Maoqi
    Chen, Liang
    BRIEFINGS IN BIOINFORMATICS, 2018, 19 (01) : 109 - 117
  • [4] Stability of methods for differential expression analysis of RNA-seq data
    Lin, Bingqing
    Pang, Zhen
    BMC GENOMICS, 2019, 20 (1)
  • [5] Novel Data Transformations for RNA-seq Differential Expression Analysis
    Zhang, Zeyu
    Yu, Danyang
    Seo, Minseok
    Hersh, Craig P.
    Weiss, Scott T.
    Qiu, Weiliang
    SCIENTIFIC REPORTS, 2019, 9 (1)
  • [6] A comparison of methods for differential expression analysis of RNA-seq data
    Soneson, Charlotte
    Delorenzi, Mauro
    BMC BIOINFORMATICS, 2013, 14
  • [7] Differential expression analysis of RNA-seq data at single-base resolution
    Frazee, Alyssa C.
    Sabunciyan, Sarven
    Hansen, Kasper D.
    Irizarry, Rafael A.
    Leek, Jeffrey T.
    BIOSTATISTICS, 2014, 15 (03) : 413 - 426
  • [8] A comparison of methods for differential expression analysis of RNA-seq data
    Charlotte Soneson
    Mauro Delorenzi
    BMC Bioinformatics, 14
  • [9] Differential expression in RNA-seq: A matter of depth
    Tarazona, Sonia
    Garcia-Alcalde, Fernando
    Dopazo, Joaquin
    Ferrer, Alberto
    Conesa, Ana
    GENOME RESEARCH, 2011, 21 (12) : 2213 - 2223
  • [10] Differential gene expression analysis using coexpression and RNA-Seq data
    Yang, Ei-Wen
    Girke, Thomas
    Jiang, Tao
    BIOINFORMATICS, 2013, 29 (17) : 2153 - 2161
12345