Targeting PBK/TOPK decreases growth and survival of glioma initiating cells in vitro and attenuates tumor growth in vivo

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作者
Mrinal Joel
Awais A. Mughal
Zanina Grieg
Wayne Murrell
Sheryl Palmero
Birthe Mikkelsen
Hege B. Fjerdingstad
Cecilie J. Sandberg
Jinan Behnan
Joel C. Glover
Iver A. Langmoen
Biljana Stangeland
机构
[1] Oslo University Hospital,Vilhelm Magnus Laboratory for Neurosurgical Research, Department of Neurosurgery and Institute of Surgical Research
[2] Institute of Basic Medical Sciences,Laboratory of Neural Development and Optical Recording (NDEVOR), Department of Physiology
[3] University of Oslo,Norwegian Center for Stem Cell Research, Department of Immunology and Transfusion Medicine
[4] Oslo University Hospital,Present Address: Department of Radiation Biology
[5] SFI-CAST Biomedical Innovation Center,undefined
[6] Oslo University Hospital,undefined
[7] Institute for Cancer Research,undefined
[8] Norwegian Radium Hospital,undefined
[9] Oslo University Hospital,undefined
来源
Molecular Cancer | / 14卷
关键词
PBK/TOPK; Glioblastoma; Tumor; shRNA; Inhibitor; Cell culture;
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