Hyperprolactinaemia in Antipsychotic-Treated Patients

被引:0
作者
Mark B. Hamner
George W. Arana
机构
[1] Medical University of South Carolina,Department of Psychiatry and Behavioral Sciences
[2] and the Ralph H. Johnson Department of Veterans Affairs Medical Center,undefined
来源
CNS Drugs | 1998年 / 10卷
关键词
Adis International Limited; Haloperidol; Clozapine; Risperidone; Olanzapine;
D O I
暂无
中图分类号
学科分类号
摘要
Elevated prolactin (PRL) levels have been considered virtually unavoidable in most patients treated with therapeutic doses of traditional antipsychotics. Clinical effects of such hyperprolactinaemia may include amenorrhoea, galactorrhoea and sexual dysfunction. For clinical symptoms, the management has involved minimising the dosage or the use of a PRL-lowering agent.
引用
收藏
页码:209 / 222
页数:13
相关论文
共 159 条
  • [21] Haykal RF(1988)Galactorrhea: subjective response by schizophrenic patients Neurol Clin 6 213-23
  • [22] Fisher JN(1991)Self-reported neuroendocrine effects of antipsychotics in women: a pilot study J Clin Psychopharmacol 11 357-61
  • [23] Goebel S(1975)Effect of psychotropic drugs on neuroendocrine function Life Sci 17 339-42
  • [24] Dietrich M(1979)The effects of phenothiazines on endocrine function: I. Patients with inappropriate lactation and amenorrhoea Am J Psychiatry 136 1550-5
  • [25] Jarry H(1988)Prolactin and neuroleptic drugs Arch Gen Psychiatry 45 789-96
  • [26] Klibanski A(1991)Serum prolactin as a correlate of clinical response to haloperidol N Engl J Med 324 746-54
  • [27] Need RM(1979)Clozapine increases rat serum prolactin levels Neuropsychobiology 5 136-42
  • [28] Beitins IZ(1995)Effect of clozapine on human serum prolactin levels Biol Psychiatry 37 52-5
  • [29] Halbreich U(1993)Clozapine for the treatment-resistant schizophrenic: a double-blind comparison with chlorpromazine Arch Gen Psychiatry 50 636-44
  • [30] Palter S(1995)Clozapine: a novel antipsychotic agent Biol Psychiatry 38 762-4