A physical map of human chromosome 14

被引：0

作者：

Thomas Brüls

Gabor Gyapay

Jean-Louis Petit

François Artiguenave

Virginie Vico

Shizen Qin

Aye Mon Tin-Wollam

Corinne Da Silva

Delphine Muselet

Delphine Mavel

Eric Pelletier

Michael Levy

Asao Fujiyama

Fumihiko Matsuda

Richard Wilson

Lee Rowen

Leroy Hood

Jean Weissenbach

William Saurin

Roland Heilig

机构：

[1] Genoscope and CNRS UMR 8030,

[2] Multimegabase Sequencing Center,undefined

[3] The Institute for Systems Biology,undefined

[4] Washington University Genome Sequencing Center,undefined

[5] RIKEN Genome Sciences Center,undefined

[6] Centre National de Genotypage,undefined

来源：

Nature | 2001年 / 409卷

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学科分类号：

摘要：

We report the construction of a tiling path of around 650 clones covering more than 99% of human chromosome 14. Clone overlap information to assemble the map was derived by comparing fully sequenced clones with a database of clone end sequences1,2 (sequence tag connector strategy). We selected homogeneously distributed seed points using an auxiliary high-resolution radiation hybrid map comprising 1,895 distinct positions. The high long-range continuity and low redundancy of the tiling path indicates that the sequence tag connector approach compares favourably with alternative mapping strategies.

引用

页码：947 / 948

页数：1

共 33 条

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