Wee1 promotes cell proliferation and imatinib resistance in chronic myeloid leukemia via regulating DNA damage repair dependent on ATM-γH2AX-MDC1

[1] Cortes J(2021)Chronic myeloid leukemia Lancet 398 1914-1926

[2] Pavlovsky C(2019)Tyrosine kinase inhibitor therapy discontinuation for patients with chronic myeloid leukaemia in clinical practice Curr Hematol Malig Rep 14 507-514

[3] Saußele S(2020)A WEE1 family business: regulation of mitosis, cancer progression, and therapeutic target J Hematol Oncol 13 126-2164

[4] Clark RE(2020)Checkpoint kinase-1 inhibition and etoposide exhibit a strong synergistic anticancer effect on chronic myeloid leukemia cell line K562 by impairing homologous recombination DNA damage repair Oncol Rep 44 2152-135

[5] Ghelli Luserna di Rorà A(2021)Targeting Wee1 kinase as a therapeutic approach in Hematological Malignancies DNA Repair (Amst) 107 103203-254

[6] Cerchione C(2006)ATR activation in response to ionizing radiation: still ATM territory Cell Div 1 7-966

[7] Martinelli G(2010)MRN and the race to the break Chromosoma 119 115-766

[8] Simonetti G(2001)DNA double-strand breaks: signaling, repair and the cancer connection Nat Genet 27 247-16

[9] Fan Z(2003)MDC1 is a mediator of the mammalian DNA damage checkpoint Nature 421 961-3164

[10] Luo H(1996)Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro Cell 87 757-323

[1] Cortes J(2021)Chronic myeloid leukemia Lancet 398 1914-1926

[2] Pavlovsky C(2019)Tyrosine kinase inhibitor therapy discontinuation for patients with chronic myeloid leukaemia in clinical practice Curr Hematol Malig Rep 14 507-514

[3] Saußele S(2020)A WEE1 family business: regulation of mitosis, cancer progression, and therapeutic target J Hematol Oncol 13 126-2164

[4] Clark RE(2020)Checkpoint kinase-1 inhibition and etoposide exhibit a strong synergistic anticancer effect on chronic myeloid leukemia cell line K562 by impairing homologous recombination DNA damage repair Oncol Rep 44 2152-135

[5] Ghelli Luserna di Rorà A(2021)Targeting Wee1 kinase as a therapeutic approach in Hematological Malignancies DNA Repair (Amst) 107 103203-254

[6] Cerchione C(2006)ATR activation in response to ionizing radiation: still ATM territory Cell Div 1 7-966

[7] Martinelli G(2010)MRN and the race to the break Chromosoma 119 115-766

[8] Simonetti G(2001)DNA double-strand breaks: signaling, repair and the cancer connection Nat Genet 27 247-16

[9] Fan Z(2003)MDC1 is a mediator of the mammalian DNA damage checkpoint Nature 421 961-3164

[10] Luo H(1996)Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro Cell 87 757-323