Therapy of metastasized cholangiocarcinoma

被引：0
作者：
Plentz, R. R. [1 ]
Vogel, A. [2 ]
机构：
[1] Med Univ Klin, Abt Innere Med 1, Tubingen, Germany
[2] Med Hochschule Hannover, Klin Gastroenterol Hepatol & Endokrinol, D-30625 Hannover, Germany
来源：
ONKOLOGE | 2015年 / 21卷 / 11期
关键词：
Cholangiocarcinoma; Chemotherapy; Targeted therapy; Locoregional therapy; Distant metastases; BILIARY-TRACT CANCER; PHASE-II TRIAL; UNRESECTABLE CHOLANGIOCARCINOMA; INTRAHEPATIC CHOLANGIOCARCINOMA; TRANSARTERIAL CHEMOEMBOLIZATION; Y-90; MICROSPHERES; GEMCITABINE; MULTICENTER; CHEMOTHERAPY; OXALIPLATIN;
D O I：
10.1007/s00761-015-2932-2
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Cholangiocarcinoma (CCA) is the second most common primary malignant liver disease after hepatocellular carcinoma. This review is based on a selective PubMed search of the literature on the treatment of CCA. In this article current palliative chemotherapy concepts, as well as new drug and locoregional therapies are explained. At the time of diagnosis more than half of the patients are no longer candidates for curative surgical therapy due to locally advanced tumors or distant metastases. During the last decades, various novel therapies have been introduced in the field of oncology; nevertheless, the number of treatment options for CCA is still limited.
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收藏
页码：1064 / 1068
页数：5
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