Photoprotective Activity of Melanin Preparations in Human Skin Exposed to UV Irradiation: Dependence on Previous Photoexposure

被引：0
|
作者：
B. A. Paramonov
I. I. Turkovskii
I. L. Potokin
N. A. Yurlova
V. Yu. Chebotarev
机构：
[1] SPb-Tekhnologiya Firm,
来源：
Bulletin of Experimental Biology and Medicine | 2002年 / 134卷
关键词：
melanin; photoprotection; photomodification; black yeast fungi;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Photoprotective effects of three melanin preparations (from black yeast fungi and Sepia sp.) were studied. These preparations in aqueous solutions (5 μg/ml, dark exposure for 7 days) demonstrated high photomodification capacity upon exposure to visible light in doses of up to 1.8 kJ/m2. Preliminary exposure of these solutions to visible light in a dose of 360 kJ/m2 notably decreased the photoprotective effect of melanins during UV exposure of the skin treated with these solutions (at UV dose of 3.4 kJ/m2). This necessitates empirical selection of the dose and storage condition of melanin preparations for attaining the optimal photoprotective effect.
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页码：366 / 369
页数：3
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