Surgical outcome of thymectomy for myasthenia gravis

被引：5

作者：

Waitande S.S. ^{[1
]}

Thankachen R. ^{[1
]}

Philip M.A. ^{[1
]}

Shukla V. ^{[1
]}

Korula R.J. ^{[1
]}

机构：

[1] Department of Thoracic and Cardiovascular Surgery, Christian Medical College and Hospital, Vellore

来源：

Indian Journal of Thoracic and Cardiovascular Surgery | 2007年 / 23卷 / 2期

关键词：

Clinical remission rate; Myasthenia gravis; Thymectomy;

D O I：

10.1007/s12055-007-0031-8

中图分类号：

学科分类号：

摘要：

Background: The medical treatment for myasthenia gravis has been reported to have remission rates as low as 15%. Thymectomy on the other hand has been reported to have clinical remission rates up to 80% and therefore has become the accepted mode of treatment. Methods: 57 patients diagnosed with myasthenia gravis underwent thymectomy at the Christian Medical College and Hospital, Vellore from January 1994 to December 2003. The aim of this study was to determine the outcome for myasthenia gravis after thymectomy. Results: Our results indicated that female sex had a better over all prognosis, Ossermann stage, I, IIA, & III was associated with higher incidence of complete clinical remission and the response to thymectomy decreased with increasing Ossermann stage. Post operative medication requirement reduced significantly as compared to the preoperative requirement. Conclusion: We therefore conclude that trans-sternal thymectomy was found to be beneficial to all patients of mild to moderate myasthenia gravis, with 70.2% patients showing improvement postoperatively. We also advocate thymectomy for ocular myasthenia gravis. © 2007 Indian Association of Cardiovascular-Thoracic Surgeons.

引用

页码：171 / 175

页数：4

共 25 条

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