Energetics of Solvation of Mono- and Polyhydric Alcohols with Mixtures of Water with Acetone

In the cases of 1-propanol, 1,2-ethanediol, and 1,2,3-propanetriol in water-acetone mixtures at 298.15 K, the structures and properties of alcohols substantially affect the enthalpies of their solvation and only slightly affect the enthalpies of their transfer from water to the mixed solvent. As the composition of the mixed solvent is varied, a compensation of changes in nonspecific and specific solvation of alcohols containing equal numbers of nonpolar and polar fragments (methanol, 1,2-ethanediol, and 1,2,3-propanetriol) is observed.