Review of Direct Oral Anticoagulants and Guide for Effective Drug Utilization

被引:0
作者
Tigran Khachatryan
Christopher Hauschild
Jason Hoff
Tahmeed Contractor
Arthur Khachatryan
Huyentran Tran
Bert Matsuo
Alan Jacobson
Anthony Hilliard
机构
[1] Loma Linda University Medical Center,International Heart Institute
[2] University of Nevada,Reno School of Medicine
[3] VA Loma Linda Health Care Systems,Department of Cardiology
来源
American Journal of Cardiovascular Drugs | 2019年 / 19卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
Direct oral anticoagulants (DOACs) have been developed as a viable and in some cases superior alternative to warfarin. These agents have overcome some of the limitations of warfarin, which has a narrow therapeutic window and many food and drug interactions. DOACs have been demonstrated to have a more predictable and reliable pharmacology and, unlike warfarin, do not require frequent monitoring of anticoagulant effect. For these reasons, the use of DOACs is increasing. Despite the many positive attributes of these agents, limitations and contraindications do exist. An understanding of the pharmacology, indications, and contraindications is therefore crucial for effective patient management. We review the available agents to aid in effective drug utilization.
引用
收藏
页码:525 / 539
页数:14
相关论文
共 50 条
[41]   Direct oral anticoagulants [J].
Bouvenot, Gilles ;
Bounhoure, Jean-Paul ;
Montastruc, Jean-Louis ;
Vacheron, Andre .
BULLETIN DE L ACADEMIE NATIONALE DE MEDECINE, 2014, 198 (06) :1157-1195
[42]   UTILIZATION OF DIRECT-ACTING ORAL ANTICOAGULANTS AT AN ACADEMIC MEDICAL CENTER [J].
Hadlock, Gregory C. ;
D'Angio, Richard ;
Koselke, Lisa K. ;
Mayasy, Shadi ;
Goot, Taylor ;
Burnett, Allison E. .
AMERICAN JOURNAL OF HEMATOLOGY, 2018, 93 (09) :E24-E24
[43]   Drug-Drug Interactions with Direct Oral Anticoagulants: Practical Recommendations for Clinicians [J].
Terrier, Jean ;
Gaspar, Frederic ;
Fontana, Pierre ;
Youssef, Daali ;
Reny, Jean-Luc ;
Csajka, Chantal ;
Samer, Caroline F. .
AMERICAN JOURNAL OF MEDICINE, 2021, 134 (08) :939-942
[44]   Prescription Utilization of the Oral Anticoagulants [J].
Theodorou, Anna A. ;
Palmieri, Anthony ;
Szychowski, John A. ;
Sehman, Marina L. ;
Swarna, Vinod .
AMERICAN JOURNAL OF PHARMACY BENEFITS, 2012, 4 (03) :120-123
[45]   Direct oral anticoagulants are an effective therapy for left ventricular thrombus formation [J].
Gama, F. ;
Freitas, P. ;
Trabulo, M. ;
Ferreira, A. ;
Andrade, M. J. ;
Matos, D. ;
Strong, C. ;
Ribeiras, R. ;
Ferreira, J. ;
Mendes, M. .
EUROPEAN HEART JOURNAL, 2019, 40 :166-166
[46]   DIRECT ORAL ANTICOAGULANTS ARE EFFECTIVE THERAPY IN TREATING LEFT VENTRICULAR THROMBI [J].
Yunis, Adil ;
Seese, Laura ;
Stearns, Blaise ;
Genuardi, Michael ;
Thoma, Floyd ;
Kilic, Arman .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2020, 75 (11) :948-948
[47]   Effective management of acute deep vein thrombosis: direct oral anticoagulants [J].
Roussin, A. .
INTERNATIONAL ANGIOLOGY, 2015, 34 (01) :16-29
[48]   Dermatosurgery in the age of novel oral anticoagulants/direct oral anticoagulants [J].
Loeser, C. ;
Nast, A. ;
Zeymer, U. .
HAUTARZT, 2019, 70 (11) :850-853
[49]   Perioperative Elective Management in Patients Treated with Direct Oral Anticoagulants - Practical Guide [J].
Gorczyca-Glowacka, Iwona ;
Wojcik, Piotr ;
Nawacki, Lukasz ;
Tomaszuk-Kazberuk, Anna ;
Gluszek, Stanislaw .
POLISH JOURNAL OF SURGERY, 2024, 96 (05) :1-7
[50]   Laboratory testing in patients treated with direct oral anticoagulants: a practical guide for clinicians [J].
Douxfils, J. ;
Ageno, W. ;
Samama, C. -M. ;
Lessire, S. ;
ten Cate, H. ;
Verhamme, P. ;
Dogne, J. -M. ;
Mullier, F. .
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2018, 16 (02) :209-219