Enhancement of complement-dependent cytotoxicity by polyvalent melanoma cell vaccine (CancerVax): Correlation with survival

被引：0
作者：
Eddy C. Hsueh
Estela Famatiga
Rishab K. Gupta
Karen Qi
Donald L. Morton
机构：
[1] From the Sonya Valley Ghidossi Vaccine Laboratory of the Roy E. Coats Research Laboratories of the John Wayne Cancer Institute at Saint John's Health Center,
来源：
Annals of Surgical Oncology | 1998年 / 5卷
关键词：
Regional melanoma; Vaccine; Complement-dependent cytotoxicity; Humoral response;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Background: Case control studies have demonstrated that administration of CancerVax, a polyvalent melanoma cell vaccine (PMCV), after complete resection of melanoma metastases produces a significant improvement in disease-free survival (DFS). Because PMCV has no direct cytotoxic effect on melanoma cells, the authors hypothesized that it prolongs survival by enhancing antibody-mediated antimelanoma cytotoxicity.
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页码：595 / 602
页数：7
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