Mechanical and thermal properties of polypeptide modified hydroxyapatite/poly(L-lactide) nanocomposites

被引：0
作者：
JunChao Wei
YanFeng Dai
YiWang Chen
XueSi Chen
机构：
[1] Nanchang University,Department of Chemistry
[2] Chinese Academy of Sciences,CAS Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry
来源：
Science China Chemistry | 2011年 / 54卷
关键词：
hydroxyapatite; poly(; -lactide); nanocomposite; surface modification;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A new type of polypeptide (poly(γ-benzyl-l-glutamate) (PBLG)) modified hydroxyapatite (HA)/poly(l-lactide) (PLLA) nanocomposites (PBLG-g-HA/PLLA) were prepared by the solvent-mixing method, and their mechanical and thermal properties were investigated. The tensile test showed that the mechanical properties of PBLG-g-HA/PLLA nanocomposites were better than that of PLLA, even a 0.3 wt% content of PBLG-g-HA in the nanocomposites could make the tensile strength 12% higher than that of the neat PLLA sample, and the tensile modulus was about 17% higher than that of the PLLA sample. The thermal gravimetric analysis (TGA) showed that the PBLG-g-HA/PLLA composites have better thermal stability than the PLLA sample. The differential scanning calorimetry (DSC) was used to characterize the effect of PBLG-g-HA on the crystallization of PLLA. The isothermal crystallization behavior showed that the half crystallization time (t1/2) of PBLG-g-HA/PLLA was much shorter than that of the PLLA sample. When the PBLG-g-HA content was 10%, t1/2 was only 18.7 min, while t1/2 of the PLLA sample was 61.4 min. The results showed that the PBLG-g-HA worked as a nucleating agent and enhanced the crystallization speed of PLLA.
引用
收藏
页码：431 / 437
页数：6
相关论文
共 120 条
[1]  
McConnell D.(1961)Relation between inorganic chemistry and biochemistry of bone mineralization Science 133 281-282
[2]  
Frajola W.J.(2001)Self-assembly and mineralization of peptide-amphiphile nanofibers Science 294 1684-1688
[3]  
Deamer D.W.(2004)Grafting RGD containing peptides onto hydroxyapatite to promote osteoblastic cells adhesion J Mater Sci-Mater Med 15 779-786
[4]  
Hartgerink J.D.(2006)Modification of hydroxyapatite nanosurfaces for enhanced colloidal stability and improved interfacial adhesion in nanocomposites Chem Mater 18 5111-5118
[5]  
Beniash E.(2005)Preparation and characterization of magnesium doped hydroxyapatite gelatin nanocomposite J Mater Chem 15 1807-1811
[6]  
Stupp S.I.(2002)Development of an artificial vertebral body using a novel biomaterial, hydroxyapatite/collagen composite Biomaterials 23 3919-3926
[7]  
Durrieu M.C.(2007)Functional scaffolds of bicontinuous, thermoresponsive J Mater Chem 17 238-242
[8]  
Pallu S.(2007)-3-phase silica/hydroxyapatite nanocomposites J Biomed Mater Res A 81A 515-522
[9]  
Guillemot F.(2007)Composites of poly(lactide- Eur Polym J 43 4053-4074
[10]  
Bareille R.(2004)-glycolide) and the surface modified carbonated hydroxyapatite nanoparticles J Control Release 95 249-256
12345678910