An antitumor boost to TH9 cells

被引:0
|
作者
Sergio A Quezada
Karl S Peggs
机构
[1] Sergio A. Quezada and Karl S. Peggs are with the Cancer Immunology Unit,Research Department of Haematology
[2] University College London Cancer Institute,undefined
[3] London,undefined
[4] UK.,undefined
来源
Nature Immunology | 2014年 / 15卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
Cells of the TH9 subset of helper T cells differentiated in the presence of interleukin 1β (IL-1β) produce large amounts of IL-9 and IL-21 in a manner dependent on the transcription factors STAT1 and IRF1 and exhibit potent anticancer effects.
引用
收藏
页码:703 / 705
页数:2
相关论文
共 50 条
  • [1] An antitumor boost to TH9 cells
    Quezada, Sergio A.
    Peggs, Karl S.
    NATURE IMMUNOLOGY, 2014, 15 (08) : 703 - 705
  • [2] A role for Th9 cells in antitumor immune response
    Laffman-Johnson, Elise
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2013, 93 (02) : 136 - 136
  • [3] Th9 cells promote antitumor immune responses in vivo
    Lu, Yong
    Hong, Sungyoul
    Li, Haiyan
    Park, Jungsun
    Hong, Bangxing
    Wang, Lijuan
    Zheng, Yuhuan
    Liu, Zhiqiang
    Xu, Jingda
    He, Jin
    Yang, Jing
    Qian, Jianfei
    Yi, Qing
    JOURNAL OF CLINICAL INVESTIGATION, 2012, 122 (11): : 4160 - 4171
  • [4] A Decade of Th9 Cells: Role of Th9 Cells in Inflammatory Bowel Disease
    Vyas, Shachi Pranjal
    Goswami, Ritobrata
    FRONTIERS IN IMMUNOLOGY, 2018, 9
  • [5] GITR AGONISTS FACILITATE ANTITUMOR RESPONSES VIA TH9 CELLS AND IL9
    不详
    CANCER DISCOVERY, 2015, 5 (10) : 1015 - 1015
  • [6] GITR costimulation redirects regulatory T cells into Th9 cells to promote antitumor immunity
    Shi, Xiaomin
    Xiao, Xiang
    Wu, Minhao
    Fan, Yihui
    Zhang, Xiaolong
    Wu, Chenglin
    Ghobrial, Rafik
    Li, Xian
    JOURNAL OF IMMUNOLOGY, 2015, 194
  • [7] Th9 Cells in Allergic Disease
    Angkasekwinai, Pornpimon
    CURRENT ALLERGY AND ASTHMA REPORTS, 2019, 19 (05)
  • [8] Th9 cells secrete BAFF
    Awe, Olufolakemi
    Jabeen, Rukhsana
    Kaplan, Mark
    JOURNAL OF IMMUNOLOGY, 2013, 190
  • [9] Th9 Cells in Allergic Disease
    Pornpimon Angkasekwinai
    Current Allergy and Asthma Reports, 2019, 19
  • [10] TH9 cells in skin disorders
    Rachael A. Clark
    Christoph Schlapbach
    Seminars in Immunopathology, 2017, 39 : 47 - 54