WDR5 inhibition halts metastasis dissemination by repressing the mesenchymal phenotype of breast cancer cells

[21] Thiery JP(2017)Transcriptional and posttranscriptional regulation of HOXA13 by lncRNA HOTTIP facilitates tumorigenesis and metastasis in esophageal squamous carcinoma cells Oncogene. 36 5392-3193

[22] Sleeman JP(2017)TWIST1-WDR5-Hottip regulates Hoxa9 chromatin to facilitate prostate Cancer metastasis Cancer Res 77 3181-37754

[23] Jordan NV(2017)PI3K/AKT-mediated upregulation of WDR5 promotes colorectal cancer metastasis by directly targeting ZNF407 Cell Death Dis 8 37740-510

[24] Johnson GL(2015)WDR5 expression is prognostic of breast Cancer outcome PLoS One 10 502-7870

[25] Abell AN(2016)WDR5 high expression and its effect on tumorigenesis in leukemia Oncotarget. 7 7864-822

[26] Micalizzi DS(2018)Overexpression of WD repeat domain 5 associates with aggressive clinicopathological features and unfavorable prognosis in head neck squamous cell carcinoma Journal of Oral Pathology & Medicine 47 811-80915

[27] Ford HL(2018)Effect of high WDR5 expression on the hepatocellular carcinoma prognosis Oncol Lett 15 605-2009

[28] Papageorgis P(2011)Interplay between HDAC3 and WDR5 is essential for hypoxia-induced epithelial-mesenchymal transition Mol Cell 43 80901-663

[29] Lambert AW(2019)Development of Personalized Therapeutic Strategies by Targeting Actionable Vulnerabilities in Metastatic and Chemotherapy-Resistant Breast Cancer PDXs Cells 8 1999-1846

[30] Ozturk S(2016)RNAi screens identify CHD4 as an essential gene in breast cancer growth Oncotarget. 7 650-663

[21] Thiery JP(2017)Transcriptional and posttranscriptional regulation of HOXA13 by lncRNA HOTTIP facilitates tumorigenesis and metastasis in esophageal squamous carcinoma cells Oncogene. 36 5392-3193

[22] Sleeman JP(2017)TWIST1-WDR5-Hottip regulates Hoxa9 chromatin to facilitate prostate Cancer metastasis Cancer Res 77 3181-37754

[23] Jordan NV(2017)PI3K/AKT-mediated upregulation of WDR5 promotes colorectal cancer metastasis by directly targeting ZNF407 Cell Death Dis 8 37740-510

[24] Johnson GL(2015)WDR5 expression is prognostic of breast Cancer outcome PLoS One 10 502-7870

[25] Abell AN(2016)WDR5 high expression and its effect on tumorigenesis in leukemia Oncotarget. 7 7864-822

[26] Micalizzi DS(2018)Overexpression of WD repeat domain 5 associates with aggressive clinicopathological features and unfavorable prognosis in head neck squamous cell carcinoma Journal of Oral Pathology & Medicine 47 811-80915

[27] Ford HL(2018)Effect of high WDR5 expression on the hepatocellular carcinoma prognosis Oncol Lett 15 605-2009

[28] Papageorgis P(2011)Interplay between HDAC3 and WDR5 is essential for hypoxia-induced epithelial-mesenchymal transition Mol Cell 43 80901-663

[29] Lambert AW(2019)Development of Personalized Therapeutic Strategies by Targeting Actionable Vulnerabilities in Metastatic and Chemotherapy-Resistant Breast Cancer PDXs Cells 8 1999-1846

[30] Ozturk S(2016)RNAi screens identify CHD4 as an essential gene in breast cancer growth Oncotarget. 7 650-663