WDR5 inhibition halts metastasis dissemination by repressing the mesenchymal phenotype of breast cancer cells

[11] Meidhof S(2017)Epithelial-to-Mesenchymal transition: epigenetic reprogramming driving cellular plasticity Trends Genetics 33 943-959

[12] Brabletz S(2015)The cancer COMPASS: navigating the functions of MLL complexes in cancer Cancer Genet 208 178-191

[13] Lehmann W(2015)Upregulated WDR5 promotes proliferation, self-renewal and chemoresistance in bladder cancer via mediating H3K4 trimethylation Sci Rep 5 8293-313

[14] Preca BT(2013)Chromatin modifications sequentially enhance ErbB2 expression in ErbB2-positive breast cancers Cell Rep 5 302-147

[15] Mock K(2016)In vivo functional platform targeting patient-derived Xenografts identifies WDR5-Myc association as a critical determinant of pancreatic Cancer Cell Rep 16 133-3316

[16] Ruh M(2018)Up-regulated WDR5 promotes gastric cancer formation by induced cyclin D1 expression J Cell Biochem 119 3304-5154

[17] Chaffer CL(2015)WDR5 supports an N-Myc transcriptional complex that drives a Protumorigenic gene expression signature in neuroblastoma Cancer Res 75 5143-10852

[18] San Juan BP(2015)The long non-coding RNA HOTTIP enhances pancreatic cancer cell proliferation, survival and migration Oncotarget. 6 10840-197

[19] Lim E(2011)Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network Cell. 145 183-750

[20] Weinberg RA(2017)CCCTC-binding factor transcriptionally targets Wdr5 to mediate somatic cell reprogramming Stem Cells Dev 26 743-5406

[11] Meidhof S(2017)Epithelial-to-Mesenchymal transition: epigenetic reprogramming driving cellular plasticity Trends Genetics 33 943-959

[12] Brabletz S(2015)The cancer COMPASS: navigating the functions of MLL complexes in cancer Cancer Genet 208 178-191

[13] Lehmann W(2015)Upregulated WDR5 promotes proliferation, self-renewal and chemoresistance in bladder cancer via mediating H3K4 trimethylation Sci Rep 5 8293-313

[14] Preca BT(2013)Chromatin modifications sequentially enhance ErbB2 expression in ErbB2-positive breast cancers Cell Rep 5 302-147

[15] Mock K(2016)In vivo functional platform targeting patient-derived Xenografts identifies WDR5-Myc association as a critical determinant of pancreatic Cancer Cell Rep 16 133-3316

[16] Ruh M(2018)Up-regulated WDR5 promotes gastric cancer formation by induced cyclin D1 expression J Cell Biochem 119 3304-5154

[17] Chaffer CL(2015)WDR5 supports an N-Myc transcriptional complex that drives a Protumorigenic gene expression signature in neuroblastoma Cancer Res 75 5143-10852

[18] San Juan BP(2015)The long non-coding RNA HOTTIP enhances pancreatic cancer cell proliferation, survival and migration Oncotarget. 6 10840-197

[19] Lim E(2011)Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network Cell. 145 183-750

[20] Weinberg RA(2017)CCCTC-binding factor transcriptionally targets Wdr5 to mediate somatic cell reprogramming Stem Cells Dev 26 743-5406