Chronic lymphocytic leukaemia

被引：0
作者：
Michael Steurer
机构：
[1] University Hospital of Internal Medicine V,
[2] Hematology and Oncology,undefined
来源：
memo - Magazine of European Medical Oncology | 2009年 / 2卷 / 2期
关键词：
CLL; R-FC; standard therapy; Bendamustin; first line therapy; relapse therapy;
D O I：
10.1007/s12254-009-0116-8
中图分类号：
学科分类号：
摘要：
The dominating clinical presentations concerning CLL at this year’s ASH meeting were given on the results of two large randomized phase III trials exploring the use of rituximab (R) in addition to fludarabine and cyclophosphamide (FC). The data of these trials as well as a phase II trial applying R-Bendamustin convincingly demonstrated the clinical benefit of chemoimmunotherapy in CLL, at least for the younger and physically fit patients without del17p.
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页码：103 / 103
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[1]  
Hallek M(2008)Immunochemotherapy with fludarabine (F), cyclophosphamide (C) and rituximab (R) versus fludarabine and cyclophosphamide (FC) improves response rates and progression-free survival of previously untreated patients with advanced chronic lymphocytic leukemia Blood 112 11-undefined
[2]  
Fingerle-Rowson G(2008)Genomic aberrations, VH mutation status and outcome after after fludarabine and cyclophosphamide (FC) or FC plus rituximab (FCR) in the CLL8 trial Blood 112 11-undefined
[3]  
Fink AM(2008)Rituximab plus fludarabine and cyclophosphamide (R-FC) vs. FC alone in relapsed/refractory CLL: final results of REACH BO17072 trial Blood 112 11-undefined
[4]  
Busch R(2008)Subcutaneous alemtuzumab (Campath) in fludarabine-refractory CLL: final results of the CLL2H trial of the GCLLSG and comprehensive analysis of prognostic markers Blood 112 11-undefined
[5]  
Stilgenbauer S(undefined)undefined undefined undefined undefined-undefined
[6]  
Zenz T(undefined)undefined undefined undefined undefined-undefined
[7]  
Winkler D(undefined)undefined undefined undefined undefined-undefined
[8]  
Bühler A(undefined)undefined undefined undefined undefined-undefined
[9]  
Robak T(undefined)undefined undefined undefined undefined-undefined
[10]  
Moiseev SI(undefined)undefined undefined undefined undefined-undefined
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