Common genetic variants at the MC4R locus are associated with obesity, but not with dietary energy intake or colorectal cancer in the Scottish population

被引：0
|
作者：
A Tenesa
H Campbell
E Theodoratou
L Dunlop
R Cetnarskyj
S M Farrington
M G Dunlop
机构：
[1] Colon Cancer Genetics Group,Department of Public Health Sciences
[2] MRC Human Genetics Unit,undefined
[3] Institute of Genetics and Molecular Medicine,undefined
[4] Western General Hospital,undefined
[5] University of Edinburgh,undefined
[6] University of Edinburgh,undefined
[7] Faculty of Health,undefined
[8] Life and Social Sciences,undefined
[9] School of Nursing,undefined
[10] Midwifery & Social Care,undefined
[11] Napier University,undefined
来源：
International Journal of Obesity | 2009年 / 33卷
关键词：
BMI; waist circumference; colon cancer; dietary energy intake; association, genetic; colorectal cancer;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：284 / 288
页数：4
相关论文
共 50 条
  • [41] Molecular genetics of human obesity-associated MC4R mutations
    Lubrano-Berthelier, C
    Cavazos, M
    Dubern, B
    Shapiro, A
    Le Stunff, C
    Zhang, SM
    Picart, F
    Govaerts, C
    Froguel, P
    Bougnères, P
    Clement, K
    Vaisse, C
    MELANOCORTIN SYSTEM, 2003, 994 : 49 - 57
  • [42] A frameshift mutation in MC4R associated with dominantly inherited human obesity
    Yeo, GSH
    Farooqi, IS
    Aminian, S
    Halsall, DJ
    Stanhope, RC
    O'Rahilly, S
    NATURE GENETICS, 1998, 20 (02) : 111 - 112
  • [43] Investigation of the Locus Near MC4R With Childhood Obesity in Americans of European and African Ancestry
    Grant, Struan F. A.
    Bradfield, Jonathan P.
    Zhang, Haitao
    Wang, Kai
    Kim, Cecilia E.
    Annaiah, Kiran
    Santa, Erin
    Glessner, Joseph T.
    Thomas, Kelly
    Garris, Maria
    Frackelton, Edward C.
    Otieno, F. George
    Shaner, Julie L.
    Smith, Ryan M.
    Imielinski, Marcin
    Chiavacci, Rosetta M.
    Li, Mingyao
    Berkowitz, Robert I.
    Hakonarson, Hakon
    OBESITY, 2009, 17 (07) : 1461 - 1465
  • [44] Rare variants in the melanocortin 4 receptor gene (MC4R) are associated with abdominal fat and insulin resistance in youth with obesity
    Galuppo, Brittany
    Mannam, Prabhath
    Bonet, Jacopo
    Pierpont, Bridget
    Trico', Domenico
    Haskell-Luevano, Carrie
    Ericson, Mark D.
    Freeman, Katie T.
    Philbrick, William M.
    Bale, Allen E.
    Caprio, Sonia
    Santoro, Nicola
    INTERNATIONAL JOURNAL OF OBESITY, 2024,
  • [45] Evaluation of the MC4R gene across eMERGE network identifies many unreported obesity-associated variants
    Bahram Namjou
    Ian B. Stanaway
    Todd Lingren
    Frank D. Mentch
    Barbara Benoit
    Ozan Dikilitas
    Xinnan Niu
    Ning Shang
    Ashley H. Shoemaker
    David J. Carey
    Tooraj Mirshahi
    Rajbir Singh
    Jordan G. Nestor
    Hakon Hakonarson
    Joshua C. Denny
    David R. Crosslin
    Gail P. Jarvik
    Iftikhar J. Kullo
    Marc S. Williams
    John B. Harley
    International Journal of Obesity, 2021, 45 : 155 - 169
  • [46] Analysis of the Impact of Common Polymorphisms of the FTO and MC4R Genes with the Risk of Severe Obesity in Saudi Arabian Population
    Cyrus, Cyril
    Ismail, Mona H.
    Chathoth, Shahanas
    Vatte, Chittibabu
    Hasen, Majd
    Al Ali, Amein
    GENETIC TESTING AND MOLECULAR BIOMARKERS, 2018, 22 (03) : 170 - 177
  • [47] Associations of Variants in FTO and Near MC4R With Obesity Traits in South Asian Indians
    Vasan, Senthil K.
    Fall, Tove
    Neville, Matthew J.
    Antonisamy, Belavendra
    Fall, Caroline H.
    Geethanjali, Finney S.
    Gu, Harvest F.
    Raghupathy, Palany
    Samuel, Prasanna
    Thomas, Nihal
    Brismar, Kerstin
    Ingelsson, Erik
    Karpe, Fredrik
    OBESITY, 2012, 20 (11) : 2268 - 2277
  • [48] Frequency of MC4R pathway variants in a large US cohort of patients with severe obesity
    Moeller, Ida
    Kleyn, Patrick
    Sleiman, Patrick
    Vaccaro, Courtney
    Hakonarson, Hakon
    Bahl, Samira
    Antao, Tiago
    Garfield, Alastair
    EUROPEAN JOURNAL OF HUMAN GENETICS, 2023, 31 : 26 - 26
  • [49] Frequency of MC4R Pathway Variants in a Large US Cohort of Patients with Severe Obesity
    Moeller, Ida Hatoum
    Boston, Patrick Kleyn
    Sleiman, Patrick
    Vaccaro, Courtney
    Hakonarson, Hakon
    Bahl, Samira
    Antao, Tiago
    Garfield, Alastair
    OBESITY, 2021, 29 : 106 - 106
  • [50] The association of MC4R rs17782313 polymorphism with dietary intake in Iranian adults
    Khalilitehrani, Azadeh
    Qorbani, Mostafa
    Hosseini, Saeed
    Pishva, Hamideh
    GENE, 2015, 563 (02) : 125 - 129
12345