Improved Natural Killer cell activity and retained anti-tumor CD8+ T cell responses contribute to the induction of a pathological complete response in HER2-positive breast cancer patients undergoing neoadjuvant chemotherapy

被引：0
作者：
E Muraro
E Comaro
R Talamini
E Turchet
G Miolo
S Scalone
L Militello
D Lombardi
S Spazzapan
T Perin
S Massarut
D Crivellari
Riccardo Dolcetti
D Martorelli
机构：
[1] CRO Aviano,Cancer Bio
[2] IRCCS,Immunotherapy Unit, Department of Translational Research
[3] National Cancer Institute,Unit of Epidemiology and Biostatistics
[4] CRO Aviano,Scientific Direction
[5] IRCCS,Department of Medical Oncology
[6] National Cancer Institute,Department of Pathology
[7] CRO Aviano,Division of Breast Surgical Oncology
[8] IRCCS,undefined
[9] National Cancer Institute,undefined
[10] CRO Aviano,undefined
[11] IRCCS,undefined
[12] National Cancer Institute,undefined
[13] CRO Aviano,undefined
[14] IRCCS,undefined
[15] National Cancer Institute,undefined
[16] CRO Aviano,undefined
[17] IRCCS,undefined
[18] National Cancer Institute,undefined
来源：
Journal of Translational Medicine | / 13卷
关键词：
Breast cancer; Neoadjuvant chemotherapy; Antitumor immunity; CD8; T lymphocytes; NK cells; Immunomonitoring; Polyfunctional T cell responses; Th17 cells; HER2-overexpression; Pathological complete response;
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