Aspirin promotes apoptosis in a murine model of colorectal cancer by mechanisms involving downregulation of IL-6–STAT3 signaling pathway

[1] Cole BF(2009)Aspirin for the chemoprevention of colorectal adenomas: meta-analysis of the randomized trials J Natl Cancer Inst 101 256-266

[2] Logan RF(2008)NSAIDs and apoptosis Cell Mol Life Sci 65 1295-1301

[3] Halabi S(2009)gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis Cancer Cell 15 91-102

[4] Benamouzig R(2009)IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer Cancer Cell 15 103-113

[5] Sandler RS(2006)Interleukin-6 trans-signalling in chronic inflammation and cancer Scand J Immunol 63 321-329

[6] Grainge MJ(2005)Persistent STAT3 activation in colon cancer is associated with enhanced cell proliferation and tumor growth Neoplasia 7 545-555

[7] Jana NR(2006)Activation of STAT3 is a marker of poor prognosis in human colorectal cancer Oncol Rep 15 1445-1451

[8] Bollrath J(2005)Expression of p-STAT3 in human colorectal adenocarcinoma and adenoma; correlation with clinicopathological factors J Clin Pathol 58 833-838

[9] Phesse TJ(2007)STAT3 mRNA and protein expression in colorectal cancer: effects on STAT3-inducible targets linked to cell survival and proliferation J Clin Pathol 60 173-179

[10] von Burstin VA(2004)Constitutive activation of Stat3 signaling pathway in human colorectal carcinoma World J Gastroenterol 10 1569-1573

[1] Cole BF(2009)Aspirin for the chemoprevention of colorectal adenomas: meta-analysis of the randomized trials J Natl Cancer Inst 101 256-266

[2] Logan RF(2008)NSAIDs and apoptosis Cell Mol Life Sci 65 1295-1301

[3] Halabi S(2009)gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis Cancer Cell 15 91-102

[4] Benamouzig R(2009)IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer Cancer Cell 15 103-113

[5] Sandler RS(2006)Interleukin-6 trans-signalling in chronic inflammation and cancer Scand J Immunol 63 321-329

[6] Grainge MJ(2005)Persistent STAT3 activation in colon cancer is associated with enhanced cell proliferation and tumor growth Neoplasia 7 545-555

[7] Jana NR(2006)Activation of STAT3 is a marker of poor prognosis in human colorectal cancer Oncol Rep 15 1445-1451

[8] Bollrath J(2005)Expression of p-STAT3 in human colorectal adenocarcinoma and adenoma; correlation with clinicopathological factors J Clin Pathol 58 833-838

[9] Phesse TJ(2007)STAT3 mRNA and protein expression in colorectal cancer: effects on STAT3-inducible targets linked to cell survival and proliferation J Clin Pathol 60 173-179

[10] von Burstin VA(2004)Constitutive activation of Stat3 signaling pathway in human colorectal carcinoma World J Gastroenterol 10 1569-1573