Diet-induced obesity leads to pro-inflammatory alterations to the vitreous humour of the eye in a rat model

被引:0
作者
Kelsey H. Collins
Walter Herzog
Raylene A. Reimer
Carol R. Reno
Bryan J. Heard
David A. Hart
机构
[1] University of Calgary,Human Performance Laboratory, Faculty of Kinesiology
[2] University of Calgary,McCaig Institute for Bone and Joint Health
[3] University of British Columbia,The Centre for Hip Health and Mobility, Department of Family Practice
[4] University of Calgary,Biomedical Engineering Program
[5] University of Calgary,Department of Biochemistry and Molecular Biology
[6] Alberta Health Services Bone and Joint Health Strategic Clinical Network,undefined
来源
Inflammation Research | 2018年 / 67卷
关键词
Obesity; Vitreous humour; NLRP3 inflammasome; Chronic inflammation; Antioxidant defense; Rat;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:139 / 146
页数:7
相关论文
共 47 条
[1]  
Collins KH(2016)A high-fat high-sucrose diet rapidly alters muscle integrity, inflammation and gut microbiota in male rats Sci Rep 6 37278-1998
[2]  
Paul HA(2015)Relationship between inflammation, the gut microbiota, and metabolic osteoarthritis development: studies in a rat model Osteoarthr Cartil 23 1989-1018
[3]  
Hart DA(2016)Response to diet-induced obesity produces time-dependent induction and progression of metabolic osteoarthritis in rat knees J Orthop Res 34 1010-57
[4]  
Reimer RA(2012)Ocular immune privilege and ocular melanoma: parallel universes or immunological plagiarism? Front Immunol 3 148-1070
[5]  
Smith IC(2003). Dysfunctional immune-privilege in morbid obesity: implications and effect of gastric bypass surgery Obes Surg 13 49-718
[6]  
Rios JL(2015)Inflammatory cytokines in general and central obesity and modulating effects of physical activity PLoS One 10 e0121971-undefined
[7]  
Collins KH(2012)IL-1β is upregulated in the diabetic retina and retinal vessels: cell-specific effect of high glucose and IL-1β autostimulation PLoS One 7 e36949-undefined
[8]  
Paul HA(2015)Elevated levels of cytokines associated with Th2 and Th17 cells in vitreous fluid of proliferative diabetic retinopathy patients PLoS One 10 e0137358-undefined
[9]  
Reimer RA(2011)Oxidative stress and diabetic complications Circ Res 107 1058-undefined
[10]  
Seerattan R-A(2007)TH17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/STAT1 Nat Med 13 711-undefined