Uterine Leiomyomas: Effects on Architectural, Cellular, and Molecular Determinants of Endometrial Receptivity

被引：0
作者：
Annu Makker
Madhu Mati Goel
机构：
[1] CSM Medical University UP (Erstwhile King George Medical University),Postgraduate Department of Pathology
来源：
Reproductive Sciences | 2013年 / 20卷
关键词：
leiomyoma; endometrial receptivity; infertility; implantation; putative markers of endometrial receptivity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Impaired endometrial receptivity is an important contributing factor to implantation failure. Uterine leiomyomas are widely prevalent steroid hormone–dependent benign tumors that act as a restraint to conception and successful outcome of pregnancies. Reports are available, which suggest that leiomyomas have negative influence on endometrial receptivity to blastocyst implantation. The aim of the present review is to provide a comprehensive picture of the current knowledge of the effect of uterine leiomyomas on the architectural, cellular, and molecular determinants of endometrial receptivity. Understanding the potential role of these factors will provide insight into the underlying mechanisms of leiomyoma-associated infertility and provide new areas for basic and translational research.
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页码：631 / 638
页数：7
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