IMETHYL: An integrative database of human DNA methylation, gene expression, and genomic variation

被引：48

作者：

Komaki S. ^{[1
]}

Shiwa Y. ^{[1
,2
,3
]}

Furukawa R. ^{[1
]}

Hachiya T. ^{[1
]}

Ohmomo H. ^{[1
,2
]}

Otomo R. ^{[1
,2
]}

Satoh M. ^{[1
,2
]}

Hitomi J. ^{[4
,5
]}

Sobue K. ^{[6
]}

Sasaki M. ^{[5
,7
]}

Shimizu A. ^{[1
]}

机构：

[1] Division of Biomedical Information Analysis, Iwate Medical University, Shiwa, Iwate

[2] Division of Biobank and Data Management, Iwate Medical University, Shiwa, Iwate

[3] Laboratory of Bioinformatics, Department of Molecular Microbiology, Faculty of Life Sciences, Setagaya, Tokyo

[4] Department of Anatomy, School of Medicine, Iwate Medical University, Shiwa, Iwate

[5] Iwate Tohoku Medical Megabank Organization, Iwate Medical University, Shiwa, Iwate

[6] Iwate Medical University, Morioka, Iwate

[7] Division of Ultrahigh Field MRI, Institute for Biomedical Sciences, Iwate Medical University, Shiwa, Iwate

来源：

Human Genome Variation | / 5卷 / 1期

关键词：

D O I：

10.1038/hgv.2018.8

中图分类号：

学科分类号：

摘要：

We launched an integrative multi-omics database, iMETHYL (http://imethyl.iwate-megabank.org). iMETHYL provides whole-DNA methylation (∼24 million autosomal CpG sites), whole-genome (∼9 million single-nucleotide variants), and whole-Transcriptome (>14 000 genes) data for CD4 + T-lymphocytes, monocytes, and neutrophils collected from approximately 100 subjects. These data were obtained from whole-genome bisulfite sequencing, whole-genome sequencing, and whole-Transcriptome sequencing, making iMETHYL a comprehensive database. © 2018 Nature Publishing Group. All rights reserved.

引用

共 13 条

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