Investigation of some acute phase protein levels in cattle infected with Brucella abortus

被引：0
作者：
Çenesiz S. [1 ]
Şahin B. [1 ]
Akpinar R.K. [2 ]
Kiliçoğlu Y. [3 ]
机构：
[1] Department of Biochemistry, Faculty of Veterinary Medicine, Ondokuz Mayıs University, Samsun
[2] T.C. Ministry of Agriculture and Forestry, Samsun Veterinary Control Institute, Bee Diseases Laboratory, Samsun
[3] T.C. Ministry of Agriculture and Forestry, Samsun Veterinary Control Institute, Serology Laboratory, Samsun
来源：
Comparative Clinical Pathology | 2023年 / 32卷 / 6期
关键词：
Acute phase protein; Brucella abortus; Brucellosis; Cattle;
D O I：
10.1007/s00580-023-03508-8
中图分类号：
学科分类号：
摘要：
Brucellosis is a chronic zoonotic disease caused by brucella strains that adversely affects human and animal health. Increases or decreases in acute phase protein (APP) levels are observed in various infective diseases in cattle. In our study, it was aimed to investigate how the change in APP levels in cattle infected with Brucella abortus and which ones can be used as a marker. In the study, blood serum and plasma of 28 brucella and 10 healthy cattle collected from various cattle farm in Samsun were used. Rose bengal plate test and complement fixation test were applied to the serums. While serum amyloid A (SAA), haptoglobin (Hp), albumin, and total protein (TP) levels were determined in the blood serums taken from the groups, fibrinogen (Fb) level was determined in the plasma. As a result of the analysis, SAA 350.2 mg/L, Hp 1.57 g/L, Fb 14.58 µg/mL, TP 8.99 g/L, and albumin 2.99 g/L were found in the group infected with B. abortus. SAA 81 mg/L, Hp 0.41 g/L, Fb 2.1 µg/mL, TP 6.21 g/L, and albumin 3.57 g/L were found in the control group. Comparing the APP levels of cattle infected with B. abortus and the cattle in the control group, the levels of SAA (P < 0.05), Hp (P < 0.05), Fb (P < 0.05), and Tp (P < 0.05) were statistically significantly higher in the infected group, while the level of albumin (P < 0.05) was found to be statistically significantly decreased. © 2023, The Author(s), under exclusive licence to Springer-Verlag London Ltd., part of Springer Nature.
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页码：963 / 970
页数：7
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