Prevalance of BRCA1 and BRCA2 mutations in familial breast cancer patients in Lebanon

被引：0

作者：

Nadine Jalkh

Jinane Nassar-Slaba

Eliane Chouery

Nabiha Salem

Nancy Uhrchammer

Lisa Golmard

Domique Stoppa-Lyonnet

Yves-Jean Bignon

André Mégarbané

机构：

[1] Université Saint-Joseph,Unité de Génétique Médicale et laboratoire associé INSERM à l’Unité UMR_S910

[2] Centre Jean Perrin,Département d'Oncogénétique

[3] Université Paris-Descartes,Génétique oncologique, Institut Curie

[4] Université Saint-Joseph,Hôpital, Inserm U830

来源：

Hereditary Cancer in Clinical Practice | / 10卷

关键词：

BRCA1; BRCA2; Breast cancer; Familial; Gene; Lebanon; Mutation;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Breast cancer is the most prevalent malignancy in women in Western countries, currently accounting for one third of all female cancers. Familial aggregation is thought to account for 5–10 % of all BC cases, and germline mutations in BRCA1 and BRCA2 account for less of the half of these inherited cases. In Lebanon, breast cancer represents the principal death-causing malignancy among women, with 50 % of the cases diagnosed before the age of 50 years.

引用

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