Nonenzymatic sensing of glucose using a carbon ceramic electrode modified with a composite film made from copper oxide, overoxidized polypyrrole and multi-walled carbon nanotubes

被引：0
作者：
Hao Yu
Xuan Jian
Jun Jin
Xiao-chen Zheng
Ran-tong Liu
Guang-cai Qi
机构：
[1] Yan’an University,College of Chemistry and Chemical Engineering
来源：
Microchimica Acta | 2015年 / 182卷
关键词：
Copper oxide; Overoxidized polypyrrole; Carbon nanotubes; Glucose; Electrocatalysis;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A carbon ceramic electrode was modified with a thin film composed of overoxidized polypyrrole, CuO and multi-walled carbon nanotubes. The surface morphology, electrochemical properties and electrocatalytic activity towards the oxidation of glucose of the modified electrode were studied in detail. Benefiting from the high electrocatalytic activity of CuO, the selectivity of OPpy film, and the fast electron transfer rate promoted by MWCNTs, this modified electrode displays good stability, selectivity, high electrocatalytic activity and a low detection limit for the determination of glucose in pH 13 solution. Under the optimum conditions, the linear range for the determination of glucose by cyclic voltammetry is from 20 μM to 10 mM, and the detection limit is 4.0 μM (at an SNR of 3). The amperometric calibration plot covers the 0.20 μM to 2.0 mM concentration range, and the detection limit is 50 nM. The highest sensitivity for the determination of glucose is 3922.6 μA mM−1 cm2.
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页码：157 / 165
页数：8
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共 145 条
[1]  
Newman JD(2005)Home blood glucose biosensors: a commercial perspective Biosens Bioelectron 20 2435-2453
[2]  
Turner APF(2005)In Vivo fluorescence detection of glucose using a single-walled carbon nanotube optical sensor: design, fluorophore properties, advantages, and disadvantages Anal Chem 77 7556-7562
[3]  
Barone PW(1992)An electrochemical capillary fill device for the analysis of glucose incorporating glucose oxidase and ruthenium (III) hexamine as mediator Electroanalysis 4 1-9
[4]  
Parker RS(2001)Capacitive detection of glucose using molecularly imprinted polymers Biosens Bioelectron 16 179-185
[5]  
Strano MS(2008)Electrochemical glucose biosensors Chem Rev 108 814-825
[6]  
Morris NA(2012)Engineering grapheme/carbon nanotube hybrid for direct electron transfer of glucose oxidase and glucose biosensor J Appl Electrochem 42 875-881
[7]  
Cardosi MF(2012)A novel non-enzymatic glucose sensor based on Cu nanoparticle modified graphene sheets electrode Anal Chim Acta 709 47-53
[8]  
Bircb BJ(2013)Non-enzymatic electrochemical sensing of glucose Microchim Acta 180 161-186
[9]  
Turner APF(2014)Advances in enzyme-free electrochemical sensors for hydrogen peroxide, glucose, and uric acid Microchim Acta 181 689-705
[10]  
Cheng ZL(2012)Well-dispersed palladium nanoparticles on graphene oxide as a non-enzymatic glucose sensor RSC Adv 2 6245-6249
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