Systemic Exposure and Implications for Lung Deposition with an Extra-Fine Hydrofluoroalkane Beclometasone Dipropionate/Formoterol Fixed Combination

[1] Bateman E.D.(2003)Combination therapy with single inhaler budesonide/formoterol compared with high dose of fluticasone propionate alone in patients with moderate persistent asthma Am J Respir Med 2 275-81

[2] Bantje T.A.(2003)Budesonide and formoterol in a single inhaler improves asthma control compared with increasing the dose of corticosteroid in adults with mild-to-moderate asthma Chest 123 1480-7

[3] Joao Gomes M.(1997)Effect of inhaled formoterol and budesonide on exacerbations of asthma. Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group N Engl J Med 337 1405-11

[4] Lalloo U.G.(2002)Evaluation of different inhaled combination therapies (EDICT): a randomised, double–blind comparison of Seretide (50/250 microg bd Diskus vs formoterol (12 microg bd) and budesonide (800 microg bd) given concurrently (both via Turbuhaler) in patients with moderate–to–severe asthma Respir Med 96 851-50

[5] Malolepszy J.(2002)Budesonide/formoterol in a single inhaler versus inhaled corticosteroids alone in the treatment of asthma Pediatr Pulmonol 34 342-78

[6] Kozma D.(2008)Global strategy for asthma management and prevention: GINA executive summary Eur Respir J 31 143-303

[7] Pauwels R.A.(2007)Advances in asthma and COPD management: delivering CFC-free inhaled therapy using Modulite technology Pulm Pharmacol Ther 20 290-9

[8] Lofdahl C.G.(2007)Beclomethasone/formoterol versus budesonide/formoterol combination therapy in asthma Eur Respir J 29 682-8

[9] Postma D.S.(2007)Beclomethasone/formoterol versus fluticasone/salmeterol inhaled combination in moderate to severe asthma Allergy 62 1182-55

[10] Ringdal N(2000)Equivalent asthma control after dose reduction with HFA-134a beclomethasone solution aerosol. Comparative Inhaled Steroid Investigation Group (CISIG) Respir Med 94 549-26

[1] Bateman E.D.(2003)Combination therapy with single inhaler budesonide/formoterol compared with high dose of fluticasone propionate alone in patients with moderate persistent asthma Am J Respir Med 2 275-81

[2] Bantje T.A.(2003)Budesonide and formoterol in a single inhaler improves asthma control compared with increasing the dose of corticosteroid in adults with mild-to-moderate asthma Chest 123 1480-7

[3] Joao Gomes M.(1997)Effect of inhaled formoterol and budesonide on exacerbations of asthma. Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group N Engl J Med 337 1405-11

[4] Lalloo U.G.(2002)Evaluation of different inhaled combination therapies (EDICT): a randomised, double–blind comparison of Seretide (50/250 microg bd Diskus vs formoterol (12 microg bd) and budesonide (800 microg bd) given concurrently (both via Turbuhaler) in patients with moderate–to–severe asthma Respir Med 96 851-50

[5] Malolepszy J.(2002)Budesonide/formoterol in a single inhaler versus inhaled corticosteroids alone in the treatment of asthma Pediatr Pulmonol 34 342-78

[6] Kozma D.(2008)Global strategy for asthma management and prevention: GINA executive summary Eur Respir J 31 143-303

[7] Pauwels R.A.(2007)Advances in asthma and COPD management: delivering CFC-free inhaled therapy using Modulite technology Pulm Pharmacol Ther 20 290-9

[8] Lofdahl C.G.(2007)Beclomethasone/formoterol versus budesonide/formoterol combination therapy in asthma Eur Respir J 29 682-8

[9] Postma D.S.(2007)Beclomethasone/formoterol versus fluticasone/salmeterol inhaled combination in moderate to severe asthma Allergy 62 1182-55

[10] Ringdal N(2000)Equivalent asthma control after dose reduction with HFA-134a beclomethasone solution aerosol. Comparative Inhaled Steroid Investigation Group (CISIG) Respir Med 94 549-26