Biomedical applications of nanotechnology

被引：135
作者：
Ramos A.P. [1 ]
Cruz M.A.E. [1 ]
Tovani C.B. [1 ]
Ciancaglini P. [1 ]
机构：
[1] Departamento de Química, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (FFCLRP), Universidade de São Paulo (USP), Ribeirão Preto, 14040-901, SP
来源：
Biophysical Reviews | 2017年 / 9卷 / 2期
基金：
巴西圣保罗研究基金会;
关键词：
Inorganic particles; Liposomes; Nanobiotechnology; Nanopatterned surfaces;
D O I：
10.1007/s12551-016-0246-2
中图分类号：
学科分类号：
摘要：
The ability to investigate substances at the molecular level has boosted the search for materials with outstanding properties for use in medicine. The application of these novel materials has generated the new research field of nanobiotechnology, which plays a central role in disease diagnosis, drug design and delivery, and implants. In this review, we provide an overview of the use of metallic and metal oxide nanoparticles, carbon-nanotubes, liposomes, and nanopatterned flat surfaces for specific biomedical applications. The chemical and physical properties of the surface of these materials allow their use in diagnosis, biosensing and bioimaging devices, drug delivery systems, and bone substitute implants. The toxicology of these particles is also discussed in the light of a new field referred to as nanotoxicology that studies the surface effects emerging from nanostructured materials. © 2017, International Union for Pure and Applied Biophysics (IUPAB) and Springer-Verlag Berlin Heidelberg.
引用
收藏
页码：79 / 89
页数：10
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