Pulmonary Hypertension in Patients with Chronic Obstructive Pulmonary DiseaseAdvances in Pathophysiology and Management

被引:0
作者
Joan Albert Barberà
Isabel Blanco
机构
[1] Universitat de Barcelona,Department of Pulmonary Medicine, Hospital Clinic
[2] CIBER de Enfermedades Respiratorias,Servei de Pneumologia
[3] Hospital Clínic,undefined
来源
Drugs | 2009年 / 69卷
关键词
Chronic Obstructive Pulmonary Disease; Pulmonary Hypertension; Pulmonary Arterial Hypertension; Chronic Obstructive Pulmonary Disease Patient; Pulmonary Artery Pressure;
D O I
暂无
中图分类号
学科分类号
摘要
Pulmonary hypertension (PH) is an important complication in the natural history of chronic obstructive pulmonary disease (COPD). Its presence is associated with reduced survival and greater use of healthcare resources. The prevalence of PH is high in patients with advanced COPD, whereas in milder forms it might not be present at rest but may develop during exercise. In COPD, PH is usually of moderate severity and progresses slowly, without altering right ventricular function in the majority of patients. Nevertheless, a small subgroup of patients (1–3%) may present with out-of-proportion PH, that is, with pulmonary arterial pressure largely exceeding the severity of airway impairment. These patients depict a clinical picture similar to more severe forms of PH and have higher mortality rates.
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页码:1153 / 1171
页数:18
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