One-pot synthesis of trisubstituted pyrazoles via multicomponent approach

被引：0

作者：

P. Santhosh

V. S. R. Chunduru

V. Rajeswar Rao

机构：

[1] National Institute of Technology,Department of Chemistry

来源：

Chemistry of Heterocyclic Compounds | 2011年 / 47卷

关键词：

acetylacetone; 3-(2-bromoacetyl)coumarins; hydrazine hydrate; phenacyl bromides; pyrazole; one-pot; multicomponent reactions;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

An efficient one-pot multicomponent reaction for the synthesis of 1-aryl- or 1-heteryl-substituted 3,5-dimethylpyrazoles with excellent yields has been described. Reaction of 3-(2-bromoacetyl)coumarins or phenacyl bromides with acetylacetone and hydrazine hydrate in ethanol afforded the corresponding 3,5-dimethylpyrazoles in good yields. All the synthesized compounds were characterized by their analytical and spectral data.

引用

页码：448 / 451

页数：3