Alveolar Soft Part Sarcoma of the Oro-Maxillofacial Region in the Pediatric Age Group: Immunohistochemical and Ultrastructural Diagnosis of Two Cases

被引：0
作者：
Rimlee Dutta
Aanchal Kakkar
Pirabu Sakthivel
Rajeev Kumar
Rachna Seth
Mehar C. Sharma
机构：
[1] All India Institute of Medical Sciences,Department of Pathology
[2] All India Institute of Medical Sciences,Departments of Otorhinolaryngology and Head & Neck Surgery
[3] All India Institute of Medical Sciences,Department of Pediatrics
来源：
Head and Neck Pathology | 2021年 / 15卷
关键词：
Alveolar soft part sarcoma; Pediatric; Head and neck; Sinonasal; Immunohistochemistry; Electron microscopy;
D O I：
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学科分类号：
摘要：
Alveolar soft part sarcoma (ASPS) is infrequent in children. While head and neck locations, including the orbit and tongue, are described, only six cases of sinonasal ASPS are reported in the literature. We report two cases of pediatric oro-maxillofacial ASPS. The first case presented as a sinonasal mass in a 13-year-old girl, while the second was a tongue lesion in a 4-year-old female. Histologic examination, TFE3 immunopositivity, and ultrastructural findings of rhomboid crystalline inclusions helped confirm the diagnosis. The diagnosis of ASPS is challenging in children and in uncommon sites like the head and neck. Patients should be routinely followed up for detection of residual or recurrent disease, particularly in cases with positive resection margins.
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页码：1303 / 1307
页数：4
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