Five cases of tonsillectomy and steroid pulse therapy for recurrent immunoglobulin A nephropathy after kidney transplantation

被引：0
作者：
Yoshie Hoshino
Yasutomo Abe
Mariko Endo
Sachiko Wakai
Hiroki Shirakawa
Osamu Hotta
Hideki Ishida
Kazunari Tanabe
Ken Tsuchiya
Kosaku Nitta
机构：
[1] Tokyo Women’s Medical University,Department of Medicine, Kidney Center
[2] Okubo Hospital,Department of Nephrology
[3] Tokyo Metropolitan Health and Medical Treatment Corporation,Department of Transplantation
[4] Okubo Hospital,Department of Urology
[5] Tokyo Metropolitan Health and Medical Treatment Corporation,undefined
[6] Hotta Osamu Clinic,undefined
[7] Tokyo Women’s Medical University,undefined
来源：
CEN Case Reports | 2014年 / 3卷 / 1期
关键词：
Recurrent IgA nephropathy; Tonsillectomy; Steroid pulse; Kidney transplantation;
D O I：
10.1007/s13730-013-0098-6
中图分类号：
学科分类号：
摘要：
Five cases of recurrent immunoglobulin A nephropathy (IgAN) after kidney transplantation were successfully treated by tonsillectomy and steroid pulse therapy (SPT). The clinical background and pathology in the five cases were different, but good results were obtained in all of them. In cases 1 and 2, mild recurrent IgAN developed and failed to remit after tonsillectomy alone, but a remission was achieved in both cases after SPT. In case 3, highly active recurrent IgAN with crescent lesions developed 13 years after kidney transplantation, and a remission was achieved after SPT. In case 4, renal biopsy specimens showed pathological findings of recurrent IgAN with tubulitis, and hematuria and proteinuria resolved after SPT. In case 5, the biopsy findings indicated recurrent IgAN with chronic rejection. Tonsillectomy was followed by resolution of the proteinuria, and a remission was achieved after SPT. In conclusion, SPT is effective in inducing a remission of recurrent IgAN when tonsillectomy alone fails.
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页码：118 / 122
页数：4
相关论文
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