Proteasome inhibitors act as bifunctional antagonists of human immunodeficiency virus type 1 latency and replication

被引:0
作者
Leia K Miller
Yoshifumi Kobayashi
Chiann-Chyi Chen
Timothy A Russnak
Yacov Ron
Joseph P Dougherty
机构
[1] The State University of New Jersey - Robert Wood Johnson Medical School,Department of Molecular Pharmacology, Rutgers
[2] The State University of New Jersey,Microbiology and Molecular Genetics Graduate Program, Graduate School of Biomedical Sciences, Rutgers
来源
Retrovirology | / 10卷
关键词
HIV-1; Viral latency; Viral replication; Proteasome inhibitors; Antiviral; Bifunctional;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 512 条
  • [1] Finzi D(1999)Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy Nat Med 5 512-517
  • [2] Blankson J(2011)Curing HIV: Pharmacologic approaches to target HIV-1 latency Annu Rev Pharmacol Toxicol 51 397-418
  • [3] Siliciano JD(2009)Interim data released from inspire study on interleukin-7 AIDS Patient Care STDs 23 987-988
  • [4] Margolick JB(2005)Depletion of latent HIV-1 infection in vivo: a proof-of-concept study Lancet 366 549-555
  • [5] Chadwick K(2008)Prolonged valproic acid treatment does not reduce the size of latent HIV reservoir AIDS 22 1125-1129
  • [6] Pierson T(2009)IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infection Blood 113 6304-6314
  • [7] Smith K(2007)Stability of the latent reservoir for HIV-1 in patients receiving valproic acid J Infect Dis 195 833-836
  • [8] Lisziewicz J(2002)Effects of interleukin-2 plus highly active antiretroviral therapy on HIV-1 replication and proviral DNA (COSMIC trial) AIDS 16 1479-1487
  • [9] Lori F(2004)The multifactorial nature of HIV-1 latency Trends Mol Med 10 525-531
  • [10] Flexner C(1994)Analysis of Tat function in human immunodeficiency virus type 1-infected low-level-expression cell lines U1 and ACH-2 J Virol 68 1993-1997