sim1000G: a user-friendly genetic variant simulator in R for unrelated individuals and family-based designs

被引:0
作者
Apostolos Dimitromanolakis
Jingxiong Xu
Agnieszka Krol
Laurent Briollais
机构
[1] Lunenfeld-Tanenbaum Research Institute,Dalla Lana School of Public Health
[2] Mount Sinai Hospital,Department of Statistical Sciences
[3] University of Toronto,undefined
[4] University of Toronto,undefined
来源
BMC Bioinformatics | / 20卷
关键词
Simulation; Sequencing; NGS; 1000 genomes; Linkage disequilibrium; Pedigree data;
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[1]  
Escalona M(2016)A comparison of tools for the simulation of genomic next-generation sequencing data Nat Rev Genet 17 459-469
[2]  
Rocha S(2015)Genetic simulation tools for post-genome wide association studies of complex diseases Genet Epidemiol 39 11-19
[3]  
Posada D(2012)Next generation analytic tools for large scale genetic epidemiology studies of complex diseases Genet Epidemiol 36 22-35
[4]  
Chen HS(2013)Genetic simulation resources: a website for the registration and discovery of genetic data simulators Bioinformatics 29 1101-1102
[5]  
Hutter CM(2015)Genetic data simulators and their applications: an overview Genet Epidemiol 39 2-10
[6]  
Mechanic LE(2011)HAPGEN2: simulation of multiple disease SNPs Bioinformatics 27 2304-2305
[7]  
Amos CI(2005)simuPOP: a forward-time population genetics simulation environment Bioinformatics 21 3686-3687
[8]  
Bafna V(2013)Simulating realistic genomic data with rare variants Genet Epidemiol 37 163-172
[9]  
Hauser ER(2015)A global reference for human genetic variation Nature 526 68-74
[10]  
Hernandez RD(2009)The sequence alignment/map format and SAMtools Bioinformatics 25 2078-2079