The Effect of Biocompatible Coating Layers on Magnetic Properties of Superparamagnetic Iron Oxide Nanoparticles

被引：0
|
作者：
M. Mikhaylova
Y. S. Jo
D. K. Kim
N. Bobrysheva
Y. Andersson
T. Eriksson
M. Osmolowsky
V. Semenov
M. Muhammed
机构：
[1] Royal Institute of Technology,Dept. of Materials Science and Engineering, Materials Chemistry Division
[2] Saint Petersburg State University,Dept. of Chemistry
[3] Uppsala University,Dept. of Materials Chemistry, Ångström Laboratory
来源：
Hyperfine Interactions | 2004年 / 156-157卷
关键词：
magnetic nanoparticles; magnetite; superparamagnetism; Mössbauer spectroscopy; biocompatible coating;
D O I：
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中图分类号：
学科分类号：
摘要：
The effect of the surface coating on the magnetic properties of superparamagnetic iron oxide nanoparticles (SPION) with 8 nm in size has been studied. Four different biocompatible coating layers are considered: poly L,L-lactic acid (PLLA), poly ε-caprolactone (PCL), bovine serum albumin (BSA) and gold. The presence of coating layer on the surface of SPION is confirmed by FT-IR spectroscopy. Mössbauer spectroscopy and magnetic susceptibility measurements show that for uncoated SPION and Au@SPION the superparamagnetic fraction is retained. The formation of clusters in the case of BSA@SPION and chain-like structure for PCL@SPION and PLLA@SPION increase the inter-particle interactions resulting in hyperfine magnetic structure observed in the Mössbauer spectra at ambient temperature.
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页码：257 / 263
页数：6
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