Plasma levels of acylated ghrelin in patients with insulinoma and expression of ghrelin and its receptor in insulinomas

被引:0
作者
Hai-Yan Wu
Nai-Shi Li
Yu-Li Song
Chun-Mei Bai
Qiang Wang
Yu-Pei Zhao
Yu Xiao
Shuang Yu
Ming Li
Yuan-Jia Chen
机构
[1] Peking Union Medical College,Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences
[2] Peking Union Medical College,Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences
[3] Peking Union Medical College,Department of Medical Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences
[4] Peking Union Medical College,Department of Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences
[5] Peking Union Medical College,Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences
来源
Endocrine | 2020年 / 68卷
关键词
Insulinoma; Ghrelin; Growth hormone secretagogue receptor (GHS-R); Insulin; Obesity; BMI;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:448 / 457
页数:9
相关论文
共 293 条
[11]  
Rothmund M(2000)The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion Endocrinology 141 4325-345
[12]  
Schwarz HP(2001)Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin Gastroenterology 120 337-1136
[13]  
Kojima M(2005)Ghrelin increases food intake in obese as well as lean subjects Int J. Obes. 29 1130-249
[14]  
Hosoda H(2008)Ghrelin is a physiological regulator of insulin release in pancreatic islets and glucose homeostasis Pharmacol. Ther. 118 239-2308
[15]  
Date Y(2011)Ghrelin acylation and metabolic control Peptides 32 2301-E316
[16]  
Nakazato M(2003)The influence of insulin on circulating ghrelin Am. J. Physiol. Endocrinol. Metab. 284 E313-1508
[17]  
Matsuo H(2010)Ghrelin inhibits insulin secretion through the AMPK-UCP2 pathway in beta cells FEBS Lett. 584 1503-5086
[18]  
Kangawa K(2001)Ghrelin, a natural GH secretagogue produced by the stomach, induces hyperglycemia and reduces insulin secretion in humans J. Clin. Endocrinol. Metab. 86 5083-4684
[19]  
van der Lely AJ(2004)Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor Proc. Natl Acad. Sci. USA 101 4679-522
[20]  
Tschöp M(2005)Ghrelin: structure and function Physiol. Rev. 85 495-3120