Calmodulin antagonists induce cell cycle arrest and apoptosis in vitro and inhibit tumor growth in vivo in human multiple myeloma

被引:0
作者
Shigeyuki Yokokura
Saki Yurimoto
Akihito Matsuoka
Osamu Imataki
Hiroaki Dobashi
Shuji Bandoh
Takuya Matsunaga
机构
[1] Kagawa University,Department of Internal Medicine, Division of Hematology, Rheumatology and Respiratory Medicine, Faculty of Medicine
来源
BMC Cancer | / 14卷
关键词
Calmodulin; Multiple myeloma; Cell cycle; Apoptosis;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 235 条
[1]  
Caers J(2008)Multiple myeloma—an update on diagnosis and treatment Eur J Haematol 81 329-343
[2]  
Vande broek I(1992)Combination chemotherapy versus melphalan and prednisolone in the treatment of multiple myeloma: an overview of published trials J Clin Oncol 10 334-342
[3]  
De Raeve H(1998)Combination chemotherapy versus melphalan plus prednisone as treatment for multiple myeloma: an overview of 6,633 patients from 27 randomized trials J Clin Oncol 16 3832-3842
[4]  
Michaux L(2000)Impact on survival of high-dose therapy with autologous stem cell support in patients younger than 60 years with newly diagnosed multiple myeloma: a population-based study. Nordic Myeloma Study Group Blood 95 7-11
[5]  
Trullemans F(2011)Thalidomide for previously untreated elderly patients with multiple myeloma: meta-analysis of 1685 individual patient data from 6 randomized clinical trials Blood 118 1239-1247
[6]  
Schots R(2008)Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma N Engl J Med 359 906-917
[7]  
Van Camp B(2007)Lenalidomide plus dexamethasone for relapsed multiple myeloma in North America N Engl J Med 357 2133-2142
[8]  
Vanderkerken K(1843)The many faces of calmodulin in cell proliferation, programmed cell death, autophagy, and cancer Biochim Biophys Acta 2014 398-435
[9]  
Gregory WM(2004)Identification of genes modulated in multiple myeloma using genetically identical twin samples Blood 103 1799-1806
[10]  
Richards MA(1991)Antiproliferative effects of the Ca2+/calmodulin antagonist B859-35 and the Ca(2+)-channel blocker verapamil on human lung cancer cell lines Carcinogenesis 12 2301-2303