Human Fetal Neural Stem Cells in Rat Brain: Effects of Preculturing and Transplantation

被引：0
作者：
A. V. Revishchin
M. A. Aleksandrova
O. V. Podgornyi
M. V. Marei
R. A. Poltavtseva
L. I. Korochkin
G. A. Stepanov
G. T. Sukhikh
机构：
[1] Russian Academy of Sciences,Institute of Problems of Ecology and Evolution
[2] Russian Academy of Sciences,N. K. Kol’tsov Institute of Developmental Biology
[3] Russian Academy of Medical Sciences,Center of Obstetrics, Gynecology, and Perinatology
[4] Russian Academy of Sciences,Institute of Gene Biology
[5] Central Institute of Traumatology and Orthopedics,undefined
来源：
Bulletin of Experimental Biology and Medicine | 2005年 / 139卷
关键词：
human brain neural stem cells; xenotransplantation; hypoxia; immunohisto-chemistry; spinal cord;
D O I：
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学科分类号：
摘要：
The fate of human fetal stem/progenitor cells transplanted into rat brain depends on conditions of preculturing (long or short) and state and site of transplantation. Human nestin-positive stem cells cultured according to the short protocol did not migrate into hypoxic and normal brain after transplantation, but actively migrated in damaged spinal cord. After transplantation of long-cultured cells into the brain mainly committed neuroblasts and solitary nestin-positive cells migrated from the site of transplantation into the brain.
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页码：213 / 216
页数：3
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