Between- and Within-Individual Sociodemographic and Psychological Determinants of PrEP Adherence Among Men Who have Sex with Men Prescribed a Daily PrEP Regimen in Wales

被引：0

作者：

David Gillespie

Marijn de Bruin

Dyfrig A. Hughes

Richard Ma

Adam Williams

Fiona Wood

Zoë Couzens

Adam Jones

Kerenza Hood

机构：

[1] Cardiff University,Centre for Trials Research, College of Biomedical & Life Sciences, School of Medicine

[2] Radboud University Medical Center,Centre for Health Economics and Medicines Evaluation

[3] Institute of Health Sciences,Division of Population Medicine and PRIME Centre Wales, College of Biomedical & Life Sciences, School of Medicine

[4] IQ Healthcare,Policy, Research and International Development

[5] Bangor University,undefined

[6] Imperial College London,undefined

[7] Cardiff University,undefined

[8] Public Health Wales NHS Trust,undefined

[9] Public Health Wales,undefined

来源：

AIDS and Behavior | 2023年 / 27卷

关键词：

HIV prevention; PrEP; Adherence; Determinants; MSM;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

We investigated the determinants of daily PrEP use and coverage of condomless anal sex (CAS) by PrEP among men who have sex with men in Wales, UK. We measured PrEP use by electronic monitors and CAS by secure online surveys. We defined PrEP use based on daily medication cap openings and coverage as CAS episodes preceded by ≥ 3 days of PrEP use and followed by ≥ 2 days of PrEP use. We included 57 participants (5463 observations). An STI diagnosis was associated with lower PrEP use but also lower PrEP coverage. Older adults had higher PrEP use. A belief that other PrEP users took PrEP as prescribed was associated with lower PrEP coverage. An STI diagnosis is an important cue for an intervention, reflecting episodes of high-risk sexual behaviour and low PrEP coverage. Other results provide a basis for the development of an evidence-informed intervention for promoting coverage of PrEP.

引用

页码：1564 / 1572

页数：8

共 74 条

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