Age, Sex, Hypertension and HDL-C Alter Serum BACE1 Activity in Cognitively Normal Subjects: Implications for Alzheimer’s Disease

被引：0
|
作者：
C. Cervellati
A. Vergallo
Alessandro Trentini
G. Campo
F. Vieceli Dalla Sega
P. Rizzo
G. Bonaccorsi
V. Rosta
C. Renzini
S. Pacifico
A. Passaro
H. Hampel
G. Zuliani
机构：
[1] University of Ferrara,Department of Translational Medicine and for Romagna
[2] Sorbonne University,Alzheimer Precision Medicine (APM), AP
[3] University of Ferrara,HP, Pitié
[4] Associazione Sammarinese di Geriatria e Gerontologia (ASGG),Salpêtrière Hospital
[5] University of Ferrara,Department of Environmental and Prevention Sciences
[6] Azienda Ospedaliero-Universitaria S. Anna,Department of Chemical and Pharmaceutical Sciences
来源：
The Journal of Prevention of Alzheimer's Disease | 2022年 / 9卷
关键词：
BACE1; Alzheimer’s disease; clinical trials; fluid biomarkers; blood;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：708 / 714
页数：6
相关论文
共 34 条
  • [1] Age, Sex, Hypertension and HDL-C Alter Serum BACE1 Activity in Cognitively Normal Subjects: Implications for Alzheimer's Disease
    Cervellati, C.
    Vergallo, A.
    Trentini, A.
    Campo, G.
    Dalla Sega, F. Vieceli
    Rizzo, P.
    Bonaccorsi, G.
    Rosta, V
    Renzini, C.
    Pacifico, S.
    Passaro, A.
    Hampel, H.
    Zuliani, G.
    JPAD-JOURNAL OF PREVENTION OF ALZHEIMERS DISEASE, 2022, 9 (04): : 708 - 714
  • [2] Endothelial BACE1: Bridging the Gap Between Hypertension and Alzheimer's Disease
    Ihara, Masafumi
    CIRCULATION RESEARCH, 2022, 130 (09) : 1342 - 1344
  • [3] Transcriptional and translational regulation of BACE1 expression - Implications for Alzheimer's disease
    Rossner, Steffen
    Sastre, Magdalena
    Bourne, Krystyn
    Lichtenthaler, Stefan F.
    PROGRESS IN NEUROBIOLOGY, 2006, 79 (02) : 95 - 111
  • [4] The increased activity of BACE1 correlates with oxidative stress in Alzheimer's disease
    Borghi, Roberta
    Patriarca, Stefania
    Traverso, Nicola
    Piccini, Alessandra
    Storace, Daniela
    Garuti, Anna
    Cirmena, Gabriella
    Odetti, Patrizio
    Tabaton, Massimo
    NEUROBIOLOGY OF AGING, 2007, 28 (07) : 1009 - 1014
  • [5] BACE1 levels are increased in plasma of Alzheimer's disease patients compared with matched cognitively healthy controls
    Manzine, Patricia Regina
    Souza, Matheus da Silva
    Cominetti, Marcia Regina
    Personalized Medicine, 2016, 13 (06) : 531 - 540
  • [6] Serum beta-secretase 1 (BACE1) activity as candidate biomarker for late-onset Alzheimer's disease
    Cervellati, Carlo
    Trentini, Alessandro
    Rosta, Valentina
    Passaro, Angelina
    Bosi, Cristina
    Sanz, Juana Maria
    Bonazzi, Stefania
    Pacifico, Salvatore
    Seripa, Davide
    Valacchi, Giuseppe
    Guerini, Remo
    Zuliani, Giovanni
    GEROSCIENCE, 2020, 42 (01) : 159 - 167
  • [7] BACE1 Function and Inhibition: Implications of Intervention in the Amyloid Pathway of Alzheimer's Disease Pathology
    Koelsch, Gerald
    MOLECULES, 2017, 22 (10)
  • [8] Molecular Dynamics and Binding Energetics of Fluspirilene With BACE1: Implications for Alzheimer's Disease Intervention
    Bhattacharya, Kunal
    Bhattacharjee, Atanu
    Chakraborty, Manodeep
    Das, Dibyajyoti
    PEPTIDE SCIENCE, 2024, 116 (04)
  • [9] BACE1 SUMOylation increases its stability and escalates the protease activity in Alzheimer's disease
    Bao, Jian
    Qin, Min
    Mahaman, Yacoubou Abdoul Razak
    Zhang, Bin
    Huang, Fang
    Zeng, Kuan
    Xia, Yiyuan
    Ke, Dan
    Wang, Qun
    Liu, Rong
    Wang, Jian-Zhi
    Ye, Keqiang
    Wang, Xiaochuan
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 115 (15) : 3954 - 3959
  • [10] Machine learning models for predicting the activity of AChE and BACE1 dual inhibitors for the treatment of Alzheimer's disease
    Dhamodharan, G.
    Mohan, C. Gopi
    MOLECULAR DIVERSITY, 2022, 26 (03) : 1501 - 1517
1234